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Pharmacology Study

Pharmacologic Principles

QuestionAnswer
The highest level a drug reaches in the body. Peak Concentration
The strength of the attraction between a drug and receptor Affinity
Decreased responsiveness as a result of repeated drug administration Tolerance
Lipid soluble drug Lipophilic
The study of drugs in humans Clinical Pharmacology
Immune system response Allergic reaction
Study of drugs and their interactions with living organisms Pharmacology
The moving of drugs and their metabolites out of the body Excretion
The body has adapted to long term drug exposure in such a way that an abstinence syndrome results if the drug is stopped Physical Dependence
The ratio of the 50% lethal dose to the 50% effective dose measures drug safety Therapeutic index
Adverse reaction caused by over dosing Toxicity
Using drugs to diagnose, prevent, or treat disease or prevention of pregnancy Therapeutics
Medicines and other chemicals that can cause birth defects teratogens
any chemical that can affect living processes drug
antagonists that bind irreversibly to receptors noncompetitive antagonists
molecules that activate receptors agonists
molecules that prevent receptor activation by endogenous regulatory molecules and drugs antagonists
the plasma level at which toxic effects begin toxic concentration
an uncommon drug response resulting from a genetic predisposition idosyncratic effect
The ability of certain medications and environmental chemicals to cause cancers carcinogenic effect
the largest effect that a drug can produce maximal efficacy
Created by: shadownurse9
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