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DNA and Replication
DNA structure, function, and replication
| Term | Definition |
|---|---|
| Complementary base pair | A matching pair of nitrogenous bases such as A = T or C = G |
| Nucleotide | A phosphate, deoxyribose sugar, and a nitrogenous base |
| Antiparallel | Two strands of the DNA molecule run in opposite directions |
| What is the function of DNA? | To code for proteins |
| What type of macromolecule or biomolecule is DNA? | A nucleic acid |
| What is the monomer of DNA? | A nucleotide |
| Where in eukaryotic cells is DNA located? | The nucleus |
| Where in prokaryotic cells is DNA located? | The cytoplasm |
| What does DNA stand for? | Deoxyribonucleic acid |
| Why is the order of bases in DNA so important? | Because a specific segment of DNA, called a gene, codes for a protein that creates a physical trait |
| What is the complementary base pair to adenine? | Thymine |
| What is the complementary base pair to thymine? | Adenine |
| What is the complementary base pair to cytosine? | Guanine |
| What is the complementary base pair to guanine? | Cytosine |
| What makes up the so-called 'backbone' of DNA? | The phosphate group and sugars |
| What makes up the 'rungs' of the DNA ladder (the part you climb)? | The nitrogenous bases |
| What is the first step in the process of replicating a cell's DNA? | To separate the double helix/unzip the double helix |
| Which enzyme is responsible for 'unzipping' the double helix? | Helicase |
| What enzyme has to lay down RNA primers so that DNA polymerase knows where to begin? | Primase |
| What is the second step in DNA replication? | RNA primase lays down primers so that DNA polymerase knows where to begin |
| Which enzyme links together the sugar-phosphate backbone of the Okazaki fragments? | Ligase |
| Which enzyme adds the new nucleotides to the template DNA strand? | DNA polymerase |
| When does DNA replication happen? | During interphase |
| Given the sequence CAAGTA, what is the complementary sequence? | GTTCAT |
| When there is an error in the replication process, what is it called? Ex: A = G instead of A = T | A mutation |
| What is the shape of the DNA molecule? | A double helix |