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Vitamins + PK

Vitamins

QuestionAnswer
Retinoids Vit A (Fat). Eyesight
Thiamine B1. Turnb Carb to Energy. EtOH and eriberi and Warnicke-Korsakoff syndrome
Riboflavin B2 = Energy
Niacin, Niacinamide B3 = Metabolize Carb. Niacin ER = take ASA to minimize skin flushing
Pantothenic acid B5
Pyridoxime B6 = Anemia
Biotin B7 = Dermatitis (skin rash)
Folic Acid B9. Preg = birth defects
Cyanocobalamin B12. Anemia
Ascorbic acid C. Scuvy (formation of spots on skins)
Ergocaliferol, Cholecalciferol Vit D (Fat)
Phylloquinone, Menaquionone Vit K (Fat. is a clotmaster.
HMG CoA (statin) dosing comparitor RAS- LPF (32-8-4-2-2-1). Can switch one to another.
(statin) has least DI Pravachol (Pravastatin)
Bile Acid CI TG > 400
ss one-half
au each ear
as left ear
ad right ear
os left eye
od right eye
ou each eye
1 pint (pt) 16 oz = 473ml
1 cup 8 oz = 240 ml
1 grain (gr) 65 mg
0.00022% w/v as ppm 2.2 ppm
BMI Weight(kg)/Height(m2)
Calories Dextroase and Lipid only (Protein = muscle building)
Protein to Nitrogen Conversion 1g Nitrogen = 1g AA x 16%
Protein requirements 0.8g/kg. ARF, Hemodialysis = higher
Sustained-Release (SR) constant active drug release over a long time (12hr or more)
Extended-Release (ER) Tab or Cap w/ SEVERAL COATING release ingredient with each coat dissolved (12hr or more)
Control-Released (CR or XL) CANNOT be cut in half or crushed. Exception drugs = Sinemet CR and Toprol XL
Delayed-Release Drug surround by enteric coating = disolved in the gut
Pharmaceutical equivalent 2 drugs have same active ingredient, strength, concentration, dosage form and route of admin
Bioequivalenece when 2 PHARMACEUTICAL equivalents have similar RATE and EXTENT of bioavalability
Digoxin therapeutic range 0.8-1.2 ng/mL
Lithium therapeutic range Acute[0.6-1.2 mEq/L] and Maintenance[0.8-1.0]
Theophyllin therapeutic range 5-15 mcg/mL
Vancomycin pk and tr Pk (20-40 mcg/mL) and Tr(5-10 mcg/mL)
Created by: _Tom_
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