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Female Repro

Goljan's Female repro

List the pathological findings of the placenta in preeclampsia. a. Premature aging of the placenta b. Multiple placental infarctions c. Atherosclerosis in spiral arteries
Gestational : Hypertension, proteinuria, edema Preeclampsia / eclampsia
Gestational : Snowstorm appearance Complete hydatidiform mole
Gestational : Uterus too large for gestational age Complete hydatidiform mole
Gestational : State the difference between the chromosome in complete mole and partial mole. Complete mole = 46XX (2 chromosome from 2 sperm) Partial mole = 69XXY (2 sperm chromosome + 1 ovum chromosome)
Gestational : What causes preeclampsia in the 1st trimester? Complete hydatidiform mole
Vulva : Bartholin gland abscess most often caused by? Neisseria gonorrhoeae
Vulva : Thinning of epidermis + Parchment-like appearance of skin Lichen sclerosis
Vulva : White plaque-like lesion Lichen simplex chronicus
Vulva : Benign tumor of apocrine sweat gland Papillary hidradenoma
Vulva : Red, crusted vulvar lesion + intraepithelial adenocarcinoma (spreads along epithelium) Extra mammary Paget's disease
Genital infection : Pruritic vaginitis + white discharge + fiery red mucosa Candida albicans
Genital infections : Newborn with conjunctivitis + pneumonia Chlamydia trachomatis
Genital infections : Malodorous vaginal discharge + clue cells Gardnerella vaginalis
Genital infections : Recurrent vesicles that ulcerate + scrapings show multinucleated cells with eosinophilic intranuclear inclusions HSV-2
Genital infections : Frothy discharge + flagellated protozoa Trichomonas vaginalis
Vagina : Anatomical cause of primary amenorrhea Rokitansky-Kuster-Hauser syndrome (absence of upper vagina and uterus)
Vagina : Cyst on lateral wall of vagina Gartner's duct cyst (remnant of wolffian duct)
Vagina : Little girls + necrotic, grape-like mass protrudes from vagina Embryonal rhabdomyosarcoma
Vagina : Tumor associated with intrauterine exposure to diethystilbestrol Clear cell adenocarcinoma of the vagina
Vagina : What pathogen cause follicular cervicitis? Chlamydia trachomatis
Interpretation of pap smear : A) Superficial squamous cells indicate? B) Intermediate squamous cells indicate? C) Parabasal cells indicate? A) adequate estrogen B) adequate progesterone C) lack of estrogen and progesterone
Hormone : Endometrial cells with subnuclear vacuoles are signs of? Ovulation
Hormone : Excess of hair in normal hair-bearing areas + male secondary sex characteristics Virilization
List the main causes of abnormal bleeding from vagina in prepubertal females. 1) Vulvovaginitis 2) Embryonal rhabdomyosarcoma
List the main causes of abnormal bleeding from vagina in female from menarche to 20 years old. 1) Anovulatory DUB 2) von Willebrand's disease
List the main causes of abnormal bleeding from vagina in female from 20 to 40 years old. 1) Complications of pregnancy 2) Ovulatory DUB 3) PID, hypothyroidism, submucosal leiomyomas, adenomyosis, endometrial polyp, endometriosis
List the main causes of abnormal bleeding from vagina in female 40 years or older. 1) Anovulatory DUB (MCC in perimenopausal period) 2) Endometrial hyperplasia/cancer
Uterine : Common pathogen for endometritis. Group B streptococcus (Streptococcus agalactiae)
Uterine : Plasma cells in the endometrium. Dx? What are the causes? Chronic endometritis Causes : -Retained placenta -Gonorrhea, intrauterine device (Actinomyces israeli)
Uterine : Dx : diffuse enlargement of uterus Adenomyosis
Uterine : Endometrial adenocarcinoma + Malignant mesenchymal tumor = ? Malignant mixed mullerian tumors (carcinosarcoma)
Fallopian tube : Cystic mullerian remnants, most often located around fimbriated end Hydatids of Morgagni
Fallopian tube : Common pathogens of PID? 1) Neisseria gonorrhea 2) Chlamydia trachomatis 3) Bacteroides fragilis, streptococci, Clostridium perfringens
Fallopian tube : Invagination of mucosa into muscle, producing nodules. Salpingitis isthmica nodosa (SIN)
Ovarian : MCC of ovarian mass in pregnancy Corpus luteum cyst
Ovarian tumors : Mucus-secreting cells + Multinucleated tumor + Pseudomyxoma peritonei Mucinous cyst-adenoma/adenocarcinoma
Ovarian tumors : Contain transitional-like epithelium (Walthard's rest) Brenner's tumors
Ovarian tumors : Has functioning thyroid tissue Struma ovarii types of Cystic teratoma
Ovarian tumors : Tumor contain muscle + neuroepithelium Immature malignant types of Cystic teratoma
Ovarian tumors : Associated with streak gonads of Turner's syndrome Dysgerminoma
Ovarian tumors : Associated with ascites and right sided pleural effusion + fluid resolves once tumor is resected Thecoma-fibroma (Meigs' syndrome = ascites, pleural effusion, benign ovarian tumor)
Ovarian tumors : Call-Exner bodies Granulosa-thecal cell tumor
Ovarian tumors : Reinke crystals Pure Leydig cell tumor
Ovarian tumors : Signet-ring cells Krukenberg tumor (which came hematogenously from gastric cancer)
Gestational : Implantation over cervical os. What is the disorder's term, and its symptoms? Placenta previa Sx = painless vaginal bleeding
Gestational : What is the term for premature seperation of placenta due to formation of retroplacental clot? Abruptio placentae Sx = painful vaginal bleeding
Gestational : What is the term for direct implantation into muscle without decidua? Placenta accreta
Gestational : What is the term for accessory lobes of placenta located along the margin? Succenturiate lobes
Gestational : List the main causes of enlarged placenta. 1) Diabetes mellitus 2) Rh hemolytic disease of newborn 3) Congenital syphilis
Gestational : What are the causes of A) Polyhydramnios? B) Oligohydramnios A) Tracheoesophageal fistula, Duodenal atresia B) Juvenile polycystic kidney disease
Gestational : What are the consequences of A) Increased maternal AFP B) Decreased maternal AFP A) Open neural tube defect B) Down syndrome
Breast : List the causes of galactorrhea. 1) Mechanical stiumation of nipple 2) Prolactinoma 3) Primary hypothyroidism 4) Drugs (ie: OCP)
Breast : List the causes of bloody nipple discharge. 1) Intraductal papilloma 2) Ductal cancer
Breast : List the cause of purulent nipple discharge. Acute mastitis due to Staphylococcus aureus
Breast : List the cause of greenish brown nipple discharge. Mammary duct ectasia (plasma cell mastitis)
Breast : Blue domed cyst Fibrocystic change
Breast : Microscopic show lipid-laden macrophages with foreign body giant cells, fibrosis, and dystrophic calcification Traumatic fat necrosis
Breast : Discrete movable breast tumor Fibroadenoma
Breast : Bulky tumor derived from stromal cells which often reach massive size Phyllodes tumor
Breast cancer : Cribiform or comedo pattern Ductal carcinoma in situ
Breast cancer : Stellate shaped Infiltrating ductal carcinoma
Breast cancer : Rash around nipple Paget's disease
Breast cancer : Bulky, soft tumor with large cells and lymphoid infiltrate + associated with BRCA 1 mutations Medullary carcinoma
Breast cancer : Neoplastic cells arranged in linear fashion or form concentric circles (bull's eye) Invasive lobular carcinoma
Breast cancer : Neoplastic cells surrounded by extracellular mucin Colloid (mucinous) carcinoma
List the pathologic causes of gynecomastia in men. 1) Cirrhosis 2) Klinefelter's syndrome 3) Drugs (ie : spironolactone)
Created by: lemontea88



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