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Endocrine (Goljan)

Endocrine - Goljan

Thyroid tumor which spreads mainly hematogenously Follicular Carcinoma of the thyroid
Thyroid : Scant colloid, papillary infolding of glands Grave's disease
Thyroid : Nodules with cells seperated by hyaline that stains congo red Medullary Carcinoma of the thyroid
Thyroid : Destruction of follicles, lymphocytic infiltrates, germinal follicle Hashimoto's thyroiditis
Thyroid : Granulomatous inflammation with giant cells Subacute Granulomatous thyroiditis
Thyroid : Fever, tender gland with painful cervical adenopathy Acute thyroiditis
Thyroid : Medullary carcinoma's tumor marker is? Calcitonin
List the causes of Primary Hyperparathyroidism 1) Adenoma 2) Primary hyperplasia 3) Carcinoma
Adrenal : What does Mycobacterium tuberculosis cause? Chronic adrenal insufficiency (Addison's)
Adrenal : What does Histoplasma capsulatum cause? Chronic adrenal insufficiency (Addison's)
Adrenal : What does Neisseria meningitidis cause? Waterhouse-Friderichsen syndrome (Acute adrenocortical insufficiency)
Adrenal : Bilateral adrenal hemorrhage Waterhouse-Friderichsen syndrome (Acute adrenocortical insufficiency)
Painful thyroid gland + i) preceded by upper respi infection? + ii) painful cervical adenopathy? i) Subacute granulomatous thyroiditis ii) Acute thyroiditis
Thyroid : Fibrous tissue replacing gland Reidel's thyroiditis
Name 3 disorders associated with MEN I syndrome 1) Pituitary adenoma 2) hyper Parathyroidism 3) Pancreatic tumor
Name 3 disorders associated with MEN IIa syndrome 1) Medullary carcinoma 2) Hyper Parathyroidism 3) Pheochormocytoma
Name 3 disorders associated with MEN IIb syndrome 1) Medullary carcinoma 2) Mucosal neuromas (lips/tongue) 3) Pheochromocytoma
Thyroid : Which thyroid tumor is associated with radiation exposure? Papillary carcinoma of the thyoird
Adrenal : What is secreted by an adrenal cortical adenoma with atrophy of the contralateral adrenal cortex? Glucocorticoids
Adrenal : What is secreted by an adrenal cortical adenoma without atrophy of the contralateral adrenal cortex? Aldosterone, or nothing (non-functioning)
Palpitations, anxiety, sweats, diastolic hypertension, headache Pheochromocytoma
Suspect pheochromocytoma, do what lab test? 24-hour urine for VMA, metanephrin or HVA.
Most common cause of precocious puberty Midline hamartoma
Sudden cessation of lactation after pregnancy Sheehan's postpartum necrosis
Name of ACTH stimulatory test. Metyrapone test
List GH stimulation test. Arginine / histidine / sleep stimulation test
Small cell carcinoma of lung associated with which endocrine disorder? SIADH
List causes of SIADH 1) Small cell carcinoma of lung 2) CNS injury 3) Drugs 4) Lung infections
Thyroid : Which disorder is a risk factor for primary B-cell malignant lymphoma of the thyroid? Hashimoto's thyroiditis
Increased T4, postpartum, thyroid gland enlarged and painless. Subacute painless lymphocytic thyroiditis
Child - mental retardation, short stature, increased weight Cretinism
Child - short stature, decreased weight Pituitary dwarfism
Elderly - Atrial fibrilation, muscle weakness, apathy, thyromegaly Apathetic hypothyroidism
What are the clinical differences between Plummer's disease and Graves'? Plummer lack exopthalamus and pretibial myxedema
Endocrine disorders associated with RET proto-oncogene Medullary carcinoma of thyroid
Rapidly aggressive thyroid cancer Anaplastic thyroid cancer
List causes of Primary hypo-parathyroidism (4) 1) Thyroid surgery 2) Autoimune 3) DiGeorge syndrome 4) Hypomagnesemia
Calcification of basal ganglia 1) Primary hypo-parathyroidism 2) Pseudo-hypoparathyroidism
List causes of Primary hyper-parathyroidism 1) Adenoma 2) Primary hyperplasia 3) Carcinoma
Endocrine : Muscle weakness, hemolysis Hypophosphatemia
Endocrine : Metastatic calcification, hypovitaminosis D Hyperphosphatemia
Adrenal : Hypertension + irsutism 11-OH deficiency
Adrenal : Hypotension + Hirsutism 21-OH deficiency
Adrenal : Hypertenstion + female hypogonadism + male pseudohermaphoditism 17-OH deficiency
List causes of Cushing's. (4) 1) Iatrogenic 2) Pituitary Cushing 3) Adrenal Cushing 4) Ectopic Cushing - SCC lung
High does dexamethasone can suppress .. Pituitary Cushing
Bilateral adrenalectomy causing enlargement of preexisting pituitary adenoma Nelson's syndrome
Hypertension, hypernatremia, hypokalemia, metabolic acidosis Conn's syndrome
Created by: lemontea88



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