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Autoantibodies/HLA

Autoantibody/HLA subtypeAssociated disorder
Antinuclear antibody (ANA) SLE; Almost everyone has this one (sensitive)
Anti-dsDNA, anti-Smith Specific for SLE
Antihistone Drug-induced lupus
Anti-IgG Rheumatoid factor (RA)
Anti-centromere, anti-Scl-70 Scleroderma (CREST), Scleroderma (diffuse)
Anti-mitochondrial 1 biliary cirrhosis
Anti-basement membrane Goodpasture's syndrome
Antigliadin, antiendomysial Celiac disease
Anti-desmoglein Pemphigus vulgaris
Anti-microsomal, antithryoglobin Hashimoto's thyroditis
Anti-Jo-1 Polymyositis, dermatomyositis
Anti-SS-A, B aka___ Anti-Ro, anti-La; Sjogrens
Anti-smooth muslce Autoimmune hepatitis
Anti-U1-RNP Mixed connective tissue
Anti-glutamate decarboxylase Type 1 diabetes mellitus
c-ANCA Wegener's granulomatosis
p-ANCA Other vasculitides
Anti-endomysial Celiac
Anti-microsomal Hashimoto
A3 Hemochromatosis
B27 PAIR (only HLA type with 2 numbers) = Psoriasis, Anklyosing spondylitis, Inflammatory, Reiter's syndrome
B8 Grave's Disease
DR2 Multiple sclerosis, hay fever, SLE, Goodpasture's
DR3 Diabetes Mellitus type 1
DR4 rheumatoid arthritis, diabetes mellitus type 1
DR5 Pernicious anemia --> B12 deficiency, Hashimoto's thyroiditis
DR7 Steroid-responsive neprhotic syndrome
Created by: ddecampo