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Disorders
Understanding the pathophysiology and the basics of the disorders. Quick points.
| Question | Answer |
|---|---|
| Iron deficiency anemia | nutritional disorder iron needed for hemoglobin production thus results in depleted RBC mass, decreased hemoglobin concentration and oxygen-carrying capacity of blood |
| Sickle cell disease | genetic disorder producing abnormal RBC's that get trapped in vasculature |
| ITP | acquired hemorrhagic disorder that results in autoimmune destruction of platelets in the spleen occurs often between 2-10 years of age but recovers in 6 months |
| Hemophilia | X-linked recessive disorder where deficiency in factors for blood coagulation |
| HIV & AIDS | most often from HIV infected mom but can be adolescents with high-risk behaviors |
| ALL | most common type and peaks at age 2-5 live 5 year rate 80% |
| AML | common in adolescents live 5 year rate of only 40% |
| Leukemia | a group of malignant disease of the bone marrow and lymphatics. blast cells are nonfunctional, can't fight infection, invade the bone marrow |
| Brain tumors | 2nd most common cancer in kids peak 5-10 years |
| Lymphomas | neoplastic diseases that develop from the lymphoid and hemopoietic systms |
| Hodgkin's | begins in lymph node and characterized by Reed-Sternberg Cells |
| Non-hodgkin's | proliferation of B or T lymphocytes |
| Wilm's tumor | embryonal cancer of kidney with average diagnosis of 2-4 years |
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