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Oncology
Leukemias
Question | Answer |
---|---|
Seen in children | ALL |
TdT+ | ALL |
Most responsive to therapy | ALL |
May spread to CNS and testes | ALL |
Auer rods | AML |
Responds to all-trans retinoic acid | M3 AML |
Most common leukemia in children | ALL |
Most common leukemia overall | CLL |
Seen in elderly >60 years old | CLL |
Generally indolent course | CLL |
Smudge cells | CLL |
Warm IgG autoimmune hemolytic anemia | CLL |
Very similar to small lymphocytic lymphoma | CLL |
Philadelphia chromosome t(9;22), bcr-abl | CML |
Blast crisis | CML |
Low leukocyte alkaline phosphatase | CML |
Responds to imatinib | CML |
Stains TRAP positive | Hairy T cell leukemia |
Only leukemia without lymphadenopathy | Hairy T cell leukemia |
Lymphoblasts predominate (pre-B or pre-T) | ALL |
Myeloblasts predominate | AML |
Lymphocytes predominate with non-antibody producing B cells | CLL |
Myeloid stem cells predominate | CML |