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SOPN Bioterrorism
| Question | Answer |
|---|---|
| Blood Agents Antidote | None, Decontamination |
| Hemopoetic Syndrome | Destruction of blood forming cells, bone marrow destruction |
| Hemopetic Syndrome Mani | Major Organ System Failure. Bone Marrow depression also effects GI cells & Neurovascular system cells |
| Best Antibiotic for Anthrax> | Ciproflaxacin "Cipro" |
| Nerve Agents Muscarinic | Pin Point pubils |
| Nerve Agents Bronchial | Respiratory Distress |
| Nerve Agents Sweat | Increased Sweat |
| Nerve Agents CNS | Convulsions, Coma, from Excess Acetycholine, Respiratory Arrest |
| Treatment for Plague | Best Antibiotic: Streptomycin |
| Is Plague Contagious | Highly, spread by rodents and infected fleas 1st degress septicemic shock & Thrombis of small arteries, 100 fatality |
| Pneumonic Plague | Occurs after inhalation of organism 100 death if no treatment |
| PS | Chloropicrin - Chocking agent |
| GF | Nerve Agent |
| GD | Soman - Nerve Agent |
| GB | Sarin - Nerve Agent |
| Action of Blister Agents | Skin red, itchy, blisters, burns 12-48 hrs, inhaled, ingested, skin. Corneal lession leads to permenant blindness |
| L | Lewisite arsenics "L" agents - Blister Agent Antidote for Dimercapol |
| CX | Phosgene Oxime - Worst Blister Agent |
| HN | Nitrogen Mustard - Blister Agent |
| GA | Tabun - Nerve Agent |
| Small Pox | Virus by person, formite, highly contagious, very stable remain outside host for a long time. |
| VX | Methylphosphonthioic Acid Most Deadly Nerve Agent |
| Chocking Agents Action | Action with phosgene massive pulmonary Edema, coughing, chocking, chest tight, Nausea, HA, Tearing, Lacrimination |
| AC | Hydrogen Cyanide - Blood Agent Non persistant |
| Blood Agent Actions | Release cyanide vapor or liquid - has immediate effects inhibits cell respiration leads to cardiac arrest |
| Treatment Nerve Agents | Immediate Decontamination with .5% bleach solution, charcoal on skin, flush eyes for at least 1hour |
| Dimercapol | Antidote is Lewisite a Blister Agent |
| C. Ricin | Toxin from seed of castor bean. Blocks protein synthesis, destroys pulmonary system |
| S/S of C. Ricin | N/V, cramps, diarrhea, vasuclar colapse, hypotension, pulmonary collapse |
| CL | Cloride - Chocking Agent |
| Ebola Contagious? | Highly. Kidney/Liver failure. Internal/external bleeding, fever, sore throat, N/V/D Isolation |
| HD | Sulfur Mustard - Blister Agent |
| Nerve Agents | Months to recover, need time to help cholinesterease time to recover inhibit the breakdown of ACT, = Increase ACT |
| Incapacitating Agents | Tear Gas |
| Persistant Vs Non-persistant | Persistant "G" Agents hr/weeks, Nonpersistant, minutes "V" agents |
| CK | Cyanogen Chloride - Blood Agent Nonpersistant |
| Difference between Small Pox and Chicken Pox | Chicken: No scaring, not superficial, usually trunk area. Small: Scaring superficial lessions one stage at a time |
| CX | Phosgene Oxime Worst Blister Agent |
| Cutaneous vs Inhalation Anthrax | Cutaneous: skin lessions to ulcers with swelling 1% fatality. Inhalation: 90-100% fatality |
| Vacines for Anthrax | Yes highly controversatial 6 shots |
| Blood Agents Action | Release Cyanide vapor or liquid has immediate effects. D/N/V/H, red lips, red nail beds, coma, Increased RR = Cardiac Arrest |
| CG | Phosgene most dangerous Chocking Agent used alot WWII |
| DP | Diphosgene Chocking Agent |
| Blister Agent Antidote | None, decontamination, except for Lewisite: antidote is Dimercaprol |
| Mani Small Pox | Malaise, fever, chills, backache, lessions to macules to papulues to crust then to scar 35% fatality |
| Botulinum Toxin Action | A neurotoxin produced by the bacteria clostridium botulinum block the release of acteycholine = Decreased ACT |
| Small Pox Vacine? | 3 - 15 shots must cover up |
| Botulinum Toxins Mani | Eye Drooping, Ptosis, weakness, lethargy, urinary retention, decreased GI = ileus, Cause of death = Respiratory Failure Pt will be A-Fib |
| Do you need to Isolate a patient with Anthrax | Nope, not contagious |
| Classic Symptom of Anthrax | Widened Midastium on CXR, Chest wall edema, hemmorhagic pleural effusion, hemmorrhagic meningitis |
| Question to Mrs. McKeon Do we need to know the countries listed on Power Point | No don't worry about countries. |