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Path T1- Eponyms

Eponyms Bl, Ht, Vasc

QuestionAnswer
Holly-Leaf shape; haemophilus; parvovirus Sickle Cell
Hb Barts newborn alpha thalassemia
ankryin; spectrin hereditary spherocytosis
bite cells taking a bite out of Heinz Body G6PD deficiency
PIGA mutation paroxysmal nocturnal hemoglobinuria
schistocytes microangiopathic hemolytic anemia;
schilling test pernicious anemia
acanthocytes abetalipoproteinemia; splenectomy
howell jolly bodies splenectomy or severe hemolytic anemia
pappenheimer bodies sideroblastic anemia; splenectomy
virchow thrombosis
Factor V Leiden mutation primary hypercoaguable state
white infart infarct that occur in end-artery circ
microthrombi DIC
von willebrand factor allows platelet adhesion at vascular site
glanzmanns thrombosthenia nl Agglutination, lack of GPIIb/IIIa
Bernard-Soulier nl Aggregation, decreased GPIb
ristocetin assess von willebrand factor function
D-Dimers significant size thrombus highly sensitive test help rule OUT Pulmonary embolism
Lamin gene defect Dilated Cardiomyopathy
impaired systolic pump dilated Cardiomyopathy
low voltage cardiomyopathy; amyloidosis; sarcoidosis restrictive Cardiomyopathy
systolic murmur; Q waves; vigorous systolic pump hypertrophic Cardiomyopathy
alcohol or postpartum cause secondary dilated Cardiomyopathy
asymetric septal hypertrophy idiopathic hypertrophic subaortic stenosis
adriamycin dilated Cardiomyopathy
mural thrombi Dilated Cardiomyopathy
myosin heavy chain gene defect hypertrophic Cardiomyopathy
febrile transfusion reaction susceptibilty leukocyte reduced RBC transfusion
allergic transfusion reaction (hives or anaphylaxis) washed RBC transfusion
room temperature storage platelet concentrate
coagulation factor replacement fresh frozen plasma
coagulation factor backup (clotting factor concentrate) cryoprecipitate
IgM mediated intravascular hemolysis; ABO target acute hemolytic transfusion reaction
IgG mediated extravacular hemolysis; Rh target delayed hemolytic transfusion reaction
hyperkalemia in transfusion pt hemolysis of donor RBC
pain at IV site AHTR
HBV most common infectious transfusion agent
law of laplace pressure = tension/radius; radius too much then tension has to increase But can only go so much then collapse
medial hypertrophy progression to subintimal fibrosis and hyalinization of blood vessel pathologic hallmark of hypertension
potter sequence oligohydramnios secondary to renal agenesis; flattened facies
rubella syndrome cataracts; deafness; heart defects
long philtrum; ASD fetal alcohol syndrome
lantern-like intranuclear inclusions parvovirus b19
rhogam erythroblastosis fetalis
collapsed immature alveoli neonatal respiratory distress syndrome
lecithin/sphingomyelin ratio neonatal respiratory distress syndrome
abdominal distension in newborn, air bubbles on x-ray necrotizing enterocolitis
failure to pass meconium hirschsprungs
recurrent pulmonary infections Male infertility
astrogliosis of brainstem; prone sleepin position sudden infant death syndrome
repeated hospitalization for 2ndary gain munchausen syndrome by proxy
Hippel Lindau syndrome or Tuberous Sclerosis hemangioma
small round blue cell tumors primitive cell type malignancies
Homer-Wright pseudorosettes neuroblastoma
WAGR syndrome Wilm's tumor; Aniridia; genital anomalies; mental retardation
Denys-Drash syndrome gonadal dysgenesis; nephropathy
macroglossia; hemihypertrophy WT-2 gene mutation; hepatoblastoma Beckwith-Weidemann
small round blue cell tumors; white male predominance Ewing sarcoma
proptosis; "strap cells" rhabdomyosarcoma
leukocoria-(white pupillary reflex) retinoblastoma
Birbeck granule (pentilaminar rods; tennis-racket-shaped bodies) Langerhans Cell Histiocytosis (X)
patent ductus arteriosus Rubella
coarctation Turners Syndrome
pulmonic stenosis Noonan's syndrome
AV Canal Trisomy 21
truncus arteriosus DiGeorge Syndrome
Eisenmenger Syndrome reversal of L2R shunt to R2L
clubbings; paradoxical embolism R2L shunt
flow murmur atrial septal defect
machinery like murmur patent ductus arteriosus
tet spells tetralogy of fallot
aschoff body acute rheumatic fever
mitral insufficiency marfans
Osler nodes bacterial endocarditis
prinzmetals coronary vasospasm leading to angina
saphenous vein bypass in left main coronary disease greatest gain in life expectancy
Q wave after MI shows? Larger it is; more chance of transmural MI
foam cells athersclerotic plaque
"vulnerable" atherosclerotic plaque thin fibrous cap of 65 microns or less
rib notching coarctation
polyarteritis nodosa all layers of vessels with acute fibrinoid necrosis
giant cell (temporal) arteritis temporal ophthalmic; cranial arteries inflamed
kawasaki's disease all layers of coronary artery inflamed
buergers syndrome arteries; veins; nerves acute inflammation
myeloperoxidase indicator of plaque destabilization
Created by: mcafej02