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Path T1- Eponyms
Eponyms Bl, Ht, Vasc
| Question | Answer |
|---|---|
| Holly-Leaf shape; haemophilus; parvovirus | Sickle Cell |
| Hb Barts | newborn alpha thalassemia |
| ankryin; spectrin | hereditary spherocytosis |
| bite cells taking a bite out of Heinz Body | G6PD deficiency |
| PIGA mutation | paroxysmal nocturnal hemoglobinuria |
| schistocytes | microangiopathic hemolytic anemia; |
| schilling test | pernicious anemia |
| acanthocytes | abetalipoproteinemia; splenectomy |
| howell jolly bodies | splenectomy or severe hemolytic anemia |
| pappenheimer bodies | sideroblastic anemia; splenectomy |
| virchow | thrombosis |
| Factor V Leiden mutation | primary hypercoaguable state |
| white infart | infarct that occur in end-artery circ |
| microthrombi | DIC |
| von willebrand factor | allows platelet adhesion at vascular site |
| glanzmanns thrombosthenia | nl Agglutination, lack of GPIIb/IIIa |
| Bernard-Soulier | nl Aggregation, decreased GPIb |
| ristocetin | assess von willebrand factor function |
| D-Dimers | significant size thrombus highly sensitive test help rule OUT Pulmonary embolism |
| Lamin gene defect | Dilated Cardiomyopathy |
| impaired systolic pump | dilated Cardiomyopathy |
| low voltage cardiomyopathy; amyloidosis; sarcoidosis | restrictive Cardiomyopathy |
| systolic murmur; Q waves; vigorous systolic pump | hypertrophic Cardiomyopathy |
| alcohol or postpartum cause | secondary dilated Cardiomyopathy |
| asymetric septal hypertrophy | idiopathic hypertrophic subaortic stenosis |
| adriamycin | dilated Cardiomyopathy |
| mural thrombi | Dilated Cardiomyopathy |
| myosin heavy chain gene defect | hypertrophic Cardiomyopathy |
| febrile transfusion reaction susceptibilty | leukocyte reduced RBC transfusion |
| allergic transfusion reaction (hives or anaphylaxis) | washed RBC transfusion |
| room temperature storage | platelet concentrate |
| coagulation factor replacement | fresh frozen plasma |
| coagulation factor backup (clotting factor concentrate) | cryoprecipitate |
| IgM mediated intravascular hemolysis; ABO target | acute hemolytic transfusion reaction |
| IgG mediated extravacular hemolysis; Rh target | delayed hemolytic transfusion reaction |
| hyperkalemia in transfusion pt | hemolysis of donor RBC |
| pain at IV site | AHTR |
| HBV | most common infectious transfusion agent |
| law of laplace | pressure = tension/radius; radius too much then tension has to increase But can only go so much then collapse |
| medial hypertrophy progression to subintimal fibrosis and hyalinization of blood vessel | pathologic hallmark of hypertension |
| potter sequence | oligohydramnios secondary to renal agenesis; flattened facies |
| rubella syndrome | cataracts; deafness; heart defects |
| long philtrum; ASD | fetal alcohol syndrome |
| lantern-like intranuclear inclusions | parvovirus b19 |
| rhogam | erythroblastosis fetalis |
| collapsed immature alveoli | neonatal respiratory distress syndrome |
| lecithin/sphingomyelin ratio | neonatal respiratory distress syndrome |
| abdominal distension in newborn, air bubbles on x-ray | necrotizing enterocolitis |
| failure to pass meconium | hirschsprungs |
| recurrent pulmonary infections | Male infertility |
| astrogliosis of brainstem; prone sleepin position | sudden infant death syndrome |
| repeated hospitalization for 2ndary gain | munchausen syndrome by proxy |
| Hippel Lindau syndrome or Tuberous Sclerosis | hemangioma |
| small round blue cell tumors | primitive cell type malignancies |
| Homer-Wright pseudorosettes | neuroblastoma |
| WAGR syndrome | Wilm's tumor; Aniridia; genital anomalies; mental retardation |
| Denys-Drash syndrome | gonadal dysgenesis; nephropathy |
| macroglossia; hemihypertrophy WT-2 gene mutation; hepatoblastoma | Beckwith-Weidemann |
| small round blue cell tumors; white male predominance | Ewing sarcoma |
| proptosis; "strap cells" | rhabdomyosarcoma |
| leukocoria-(white pupillary reflex) | retinoblastoma |
| Birbeck granule (pentilaminar rods; tennis-racket-shaped bodies) | Langerhans Cell Histiocytosis (X) |
| patent ductus arteriosus | Rubella |
| coarctation | Turners Syndrome |
| pulmonic stenosis | Noonan's syndrome |
| AV Canal | Trisomy 21 |
| truncus arteriosus | DiGeorge Syndrome |
| Eisenmenger Syndrome | reversal of L2R shunt to R2L |
| clubbings; paradoxical embolism | R2L shunt |
| flow murmur | atrial septal defect |
| machinery like murmur | patent ductus arteriosus |
| tet spells | tetralogy of fallot |
| aschoff body | acute rheumatic fever |
| mitral insufficiency | marfans |
| Osler nodes | bacterial endocarditis |
| prinzmetals | coronary vasospasm leading to angina |
| saphenous vein bypass in left main coronary disease | greatest gain in life expectancy |
| Q wave after MI shows? | Larger it is; more chance of transmural MI |
| foam cells | athersclerotic plaque |
| "vulnerable" atherosclerotic plaque | thin fibrous cap of 65 microns or less |
| rib notching | coarctation |
| polyarteritis nodosa | all layers of vessels with acute fibrinoid necrosis |
| giant cell (temporal) arteritis | temporal ophthalmic; cranial arteries inflamed |
| kawasaki's disease | all layers of coronary artery inflamed |
| buergers syndrome | arteries; veins; nerves acute inflammation |
| myeloperoxidase | indicator of plaque destabilization |
Created by:
mcafej02
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