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OPT Cysts
| Term | Definition |
|---|---|
| dentigerous cysts | cyst that arises from lining of follicular epithelium around the crown of an impacted tooth, most common developmental cyst; causes bone expansion, swelling, and misplaced teeth |
| eruption cyst | soft-tissue version of dentigerous cyst; blue-purple mass above erupting teeth |
| odontogenic keratocyst (OKC) | cyst that arises from rests of dental lamina aka {keratocystic odontogenic tumor}; large growth potential, high recurrence rate and associated with {Nevoid Basal Cell Carcinoma} -does not create a bony expansion, diagnosis based on microscopic features |
| Nevoid Basal Cell Carcinoma (Gorlin syndrome) | mutation of {PTCH (patched) gene}, tumor suppressor gene; basal cell carcinomas of skin, OKC of jaws, bifid ribs, calcification of falx cerebri -palmar/plantar pitting, ovarian cysts, medulloblastoma |
| palmar/plantar pitting | pits of palms and soles, from fruste of basal cell carcinoma; seen in Nevoid Basal Cell Carcinoma |
| primordial cyst | cyst that develops where tooth should have been; probably an OKC |
| orthokeratinized odontogenic cyst | like an OKC but lower recurrence and develops with impacted tooth |
| gingival cyst of the newborn | small, superficial keratin-filled cyst on alveolar ridge of infant |
| gingival cyst of the adult | small swelling of attached gingiva, blue/gray in colon in lower premolar/canine area; may cause cupping of underlying bone |
| lateral periodontal cyst | occur between roots of vital teeth (lateral radicular cyst are nonvital); most in lower premolar/canine area |
| botryoid odontogenic cyst (BOC) | multi compartment variant of lateral periodontal cyst; grape-like cluster of cysts |
| calcifying odontogenic cyst (Gorlin cyst) | cyst with cystic and solid variants; has unique eosinophilic cells lacking nuclei that can calcify, called {ghost cells} |
| dentinogenic ghost cell tumor | solid variant of calcifying odontogenic cyst |
| ghost cells | unique eosinophilic cells without nuclei that can calcify in calcifying odontogenic cysts |
| glandular odontogenic cyst | gland-like differentiation with significant recurrence rate, in anterior mandible or upper canine |
| buccal bifurcation cyst | inflammatory cyst on buccal of lower first molar, sometimes with enamel projection |
| paradental cyst | specific type of buccal bifurcation cyst associated with partially erupted third molars with pericoronitis |
| 1. de novo from remnants of dental lamina 2. malignant transformation of ameloblastoma 3. lining of odontogenic cysts | carcinoma arising in odontogenic cysts arise from: |
| ameloblastoma | 2nd most common neoplasm after odontoma; most are solid/multicystic type (conventional) that produces painless expansion of the jaw with radiographic "soap bubble" appearance with an impacted tooth |
| follicular type | most common conventional ameloblastoma; islands of epithelium that look like developing enamel, can undergo cystic change |
| plexiform type | conventional type of ameloblastoma, seen more in maxilla; cells in sheets |
| acanthomatous type | conventional type of ameloblastoma, like follicular cyst but with squamous differentiation |
| granular cell type | conventional ameloblastoma that sometimes has eosinophilic cells |
| desmoplastic type | conventional ameloblastoma with mixed radiographic lesion |
| basal cell type | least common conventional ameloblastoma, resembles basal cell carcinoma of skin |
| unicystic ameloblastoma | ameloblastoma seen in young people that mimics dentigerous cysts; {luminal, intraluminal, and mural types} |
| peripheral ameloblastoma | ameloblastoma that develops from dental lamina or basal layer of gingiva; small, fibroma-like mass on gingiva |
| malignant ameloblastoma | neoplasm with same features of ameloblastoma but metastasized to lymph node or lung |
| ameloblastic carcinoma | ameloblastoma with cytologic features of malignancy in primary tumor |
| clear cell odontogenic carcinoma | tumors of nests and cords of clear cells much like muco-ep, mostly in mandible |
| adenomatoid odontogenic tumor | tumor in anterior mandible associated with unerupted canines, sometimes contains 'snowflake' calcifications with thick capsule |
| calcifying epithelial odontogenic tumor (Pindborg tumor) | tumor that forms amyloid-like product that can calcify and form rings {Liesegang ring calcification}; cells look like stratum intermedium |
| Liesegang ring calcification | amyloid-like product that can calcify and form rings in calcifying epithelial odontogenic tumor |
| squamous odontogenic tumor | tumor from epithelial rests of Malassez so must associate with roots; epithelial islands with micro cysts |
| odontoma | most common odontogenic tumor, associated with unerupted teeth |
| compound odontoma | multiple, small tooth-like structures in anterior maxilla |
| complex odontoma | odontoma with haphazard arrangement of dental soft tissue, can be large and usually in posterior |
| ameloblastic fibroma | true neoplasm of odontogenic epithelium and ectomesenchyme associated with unerupted teeth |
| ameloblastic fibro-odontoma | mixed tumor of odontoma and ameloblastic fibroma associated with unerupted teeth in posterior mandible |
| ameloblastic fibrosarcoma | CT component exhibits cellular malignancy, often arises from ameloblastic fibroma |
| odontoameloblastoma | neoplasm of combination of odontoma and ameloblastoma |
| odontogenic myxoma | jaw tumor, gelatinous mass when excised; radiograph looks like spider web |
| central odontogenic fibroma | tumor with palatal depression, blind-ended fistula or cleft; can resorb roots |
| peripheral odontogenic fibroma | soft tissue counterpart of central odontogenic fibroma but more common; pink mass on mandibular gingiva can include cementoid-like calcifications |
| granular cell odontogenic tumor | less than 50 cases of this odontogenic tumor reported |
| cementoblastoma | identical to osteoblastoma but on roots of teeth |
Created by:
aharnold
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