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Pharm T3-missed
Pharm T3missed
Question | Answer |
---|---|
Proton Pump Inhib given when | 30-60min before meal |
Fenofibrate-R | PPAR alpha |
Cyclosporine | highest variability bioavailability, not eliminated in urine, not recycled in GI |
When acute rejection doesn't respond to Corticosteroid tx | use Muromab CD3 |
Metformin | Tx for TypeIIDM, post [Cr] eval |
"honeymoon" phase of TIDM dose | 1/2 nl |
TIDM the DCCTrial showed that | 3+ injection/d-> dec LT complications |
LMWH | has more predictable Anti-coag response |
Highest glucocort v. mineralcort ratio | Dexamethasone |
Asthma not tx with | H1 Antagonist |
Nicotinic acid [AntiHyperlipidemic] | MOA depends on dec lipolysis and FFA release |
Amylin mimetic [pramlintide] | peptide sec w/ insulin, inject b4 meal to dec Glu post meal |
Acarbose | post prandial Hyperglycemia tx |
Nicotinic acid [AntiHyperlipidemic] | least dependent on Hepatic LDL-R upregulation |
Fenofibrate+Nicotinic acid | Pt w/TG>500mg/dL, need dec acute Pancreatitis |
Ferrous SO4[o] | multi-pharm pt w/ anemia Fe<30 |
Pt 10yr diab hist, fast H-Glu, inj 2x/d, NPH+reg b4 dinner. Problems with low Glu | change time of NPH b4 bed |
Smoker, essential HTN, LDL 150 w/ Simvastatin, dec to 130 w/ | Ezetimibe add to simvastatin |
Seasonal allergy on cimetidene [P450 inhibitor] | tx w/ Fexofenadin |
inc LDL, want pregnancy, Fam Hist MI, essent HTN, dec HDL | tx w/ Colesevelam |
Hursutism, gingival Hyperplasia, renal transplant | AE of Cyclosporin |
OsteoArth, inc menses, Hct=31, no ulcer | tx w/ Indomethacin |
Fe toxicity | tx w/ Deferoxamine, not Citrate |
inc A1c, SFU+Metformin, favored 'add on" target post meal hyperGlu | Exenatide |
Allergy, truck driver, Hist-R Antagonist | Loratidine |
N/V, coffee grounds, peptic ulcer, no H. Pylori | tx w/ Omeprazole |
inc Cholest, inc K+, dark urine myoglobin, inc CK, AE of | Simvastatin |
Gout<1.3mg/dL, no urate stone but kidney stone | tx w/ Indomethacin |
Gout inc Freq and severity, 8mg | Ibuprofen+Probenicid |
Rapid Anti-coag, prevent DVT in prior Hep-induced Thrombocyt | Bivalirubin IV |
TIDM, inc risk of hypoGlu, need post-prandial insulin flexibility | Subst Lispro for Reg |
TIDM, inc risk of hypoGlu, need basal insulin | Subst Glargine for NPH |
Which AE is there no tolerance to | miosis |
hypokalemia, HTN, dec renin, HyperCort | tx w/ spironolactone |
tx w/ Sumatriptan failed acutely-> headache | Subst tx w/ Elitriptan[acutely]/TCA amitryptin [prophylaxis] |
Thiaolidine+Rosiglitazone | inc risk of ht attack, MOA dec insulin Resist and dec FFA |
Biguanide/Metformin | inhibit Hepatic GNG thru activating AMPK |
SFU[glipizide] | Ca channle blker and Diuretic interfere with MOA |
Metformin | does not lead to wt gain or hypoglycemia |
Metformin | 1st line Type 2 DM |
Induction phase of Immunosuppression | Corticosteroid, MM, Tacrolimus |
Opioids | do not activate Glumate[E]-R |
Opioids | dec Ca conduction, dec cAMP, inc K conduction, activat Gi/o |
LMWH | require AT III, have a long t1/2, lesser inhib of Thromb, dec thrombocytopenia risk |
Anti-Inflammatory inject directly to joint | Triamcinolone Acetamide |
Flutamide | dec Androgen activation at R |
Flutamide | does not dec 5aReductase, dec FSH/LH/GnRH |
Acarbose | specifically target post meal HyperGlu in pre-diabetics |
Celecoxib | tx underlying coz of OA in Pt wit Hx PUD |
multi-pharm female w/ anemia | FeSO4 IM |
Chronic tx for IBD/UC | Mesalamine 5-ASA |
M. Relaxers given with fentanyl to dec | Truncal rigidity |
Greatly dec LDL, mild dec TG and vLDL | Rosuvastatin |
Confirmatory test for Gout v other inflamm dz | Colchicine |
Metformin | AE: inc risk of Metabolic Acidosis, temporary d/c if dye used |