click below
click below
Normal Size Small Size show me how
Effects of tumors
Paraneoplastic effects of tumors
Neoplasm | Causes | Effect |
---|---|---|
Small cell lung carcinoma and intracranial neoplasms | ADH | SIADH |
Squamous cell lung carcinoma, renal cell carcinoma, breast carcinoma | PTH-related peptide, TGF-B, TNF, IL-1 | Hypercalcemia |
Renal cell carcinoma, hemanigioblastoma | Erythropoietin | Polycythemia |
Thymoma, small cell lung carcinoma | Antibodies against presynaptic Ca channels at neuromuscular junction | Lambert-Eaton syndrome (muscle weakness) |
Leukemias and lymphomas | Hyperuricemia, due to excess nuclei acid turnover (cytotoxic therapy) | Gout, urate nephropathy |
Small cell lung carcinoma | ACTH, ACTH-like peptide | Cushing's syndrome |