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Effects of tumors

Paraneoplastic effects of tumors

NeoplasmCausesEffect
Small cell lung carcinoma and intracranial neoplasms ADH SIADH
Squamous cell lung carcinoma, renal cell carcinoma, breast carcinoma PTH-related peptide, TGF-B, TNF, IL-1 Hypercalcemia
Renal cell carcinoma, hemanigioblastoma Erythropoietin Polycythemia
Thymoma, small cell lung carcinoma Antibodies against presynaptic Ca channels at neuromuscular junction Lambert-Eaton syndrome (muscle weakness)
Leukemias and lymphomas Hyperuricemia, due to excess nuclei acid turnover (cytotoxic therapy) Gout, urate nephropathy
Small cell lung carcinoma ACTH, ACTH-like peptide Cushing's syndrome
Created by: ddecampo