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Pharm test 1 drugs
Test 1 drugs- cholinergic, anticholinergic lilk8tob
| Name | Info |
|---|---|
| bethanechol (Urecholine) general class: | cholinergic |
| bethanechol (Urecholine)- direct or indirect acting: | direct acting |
| bethanechol (Urecholine)- drug effect: | increased bladder tone, increased motility |
| bethanechol (Urecholine)- uses | treatment of nonobstructive urinary retention; GI retention |
| bethanechol (Urecholine) side effects: | Not for use w/ hyperthyroidism, peptic ulcer, bronchial asthma, epilepsy |
| donepezil (Aricept)- general class: | cholinergic |
| donepezil (Aricept)- direct or indirect: | anticholinesterase (indirect acting) |
| donepezil (Aricept)- drug effect: | increases levels of ACh in brain by preventing its breakdown |
| donepezil (Aricept)- uses: | mild to moderate Alzheimer's |
| donepezil (Aricept)- SE | avoid drugs w/ anticholinergic properties |
| physostigmine (Antilirium)- general class: | cholinergic |
| hysostigmine (Antilirium)- direct or indirect: | anticholinesterase (indirect acting) |
| hysostigmine (Antilirium)- drug effect: | incrases ACh by inhibiting AChE; improves muscle strength |
| hysostigmine (Antilirium)- uses | myastenia gravis, TCA overdose |
| hysostigmine (Antilirium)- SE: | caution w/ epilepsy, bronchial asthma, bradycardia, hyperthyroidism, dysrhythmies, peptic ulcer |
| atropine- general class: | cholinergic-blocking |
| atropine- natural/synthetic: | naturally occurring anticholinergic |
| atropine- drug effect | cholinergic blocking effects on heart and smooth muscles of bronchi & intestines |
| atropine- uses | preop (reduces secretions), bradycardia |
| atropine- SE: | angle-closure glaucoma, adhesions between iris &lens, some types of asthma, ulcerative colitis |
| dicyclomine (Bentyl)- general class: | cholinergic-blocking |
| dicyclomine (Bentyl)- natural/synthetic | synthetic anticholinergic |
| dicyclomine (Bentyl)- drug effect | antispasmodic cholinergic blocker |
| dicyclomine (Bentyl)- uses | functional disturbances of GI motility *IBS*, infant colic |
| dicyclomine (Bentyl)- SE | GI obstruction, myasthenia gravis, narrow-angle glaucoma |
| scopalamine (Transderm Scop)- general class | cholinergic-blocking |
| scopalamine (Transderm Scop)- natural/synthetic | naturally occurring anticholinergic |
| scopalamine (Transderm Scop)- drug effect | corrects the imbalance between ACh and NE in the brain (especially the vomit center) |
| scopalamine (Transderm Scop)- uses | motion sickness, preop for control of secretions |
| albuterol (Ventolin)- general class | adrenergic |
| albuterol (Ventolin)- category | selective beta2 adrenergic |
| albuterol (Ventolin)- drug effect | bronchodilator |
| albuterol (Ventolin)- uses | asthma |
| epinephrine (Adrenalin)- general class | adrenergic |
| epinephrine (Adrenalin)- category | nat. occurring catecholamine, produced by adrenal medulla; mixed alpha & beta |
| epinephrine (Adrenalin)- drug effect | vasoconstriction, increased BP, cardiac stimulation, dilation of bronchioles |
| epinephrine (Adrenalin)- uses | acute asthma attack, anaphylaxis, restore cardiac rhythm in cardiac arest, nasal decongestant |
| epinephrine (Adrenalin)- SE | not for: narrow-angle glaucoma, shock from trauma, coronary insufficiency, labor |
| pseudoephedrine (Afrin)- general class | adrenergic |
| pseudoephedrine (Afrin)- category | natural plant alkaloid |
| pseudoephedrine (Afrin)- drug effect | decongestant (nasal), orally administered |
| pseudoephedrine (Afrin)- uses | congested nose |
| pseudoephedrine (Afrin)- SE | ephedra is a component of certain OTC herbal dietary supplements, so it is unsafe to use both |
| dobutamine (Dobutrex)- general class | adrenergic |
| dobutamine (Dobutrex)- category | beta1-selective vasoactive adrenergic drug |
| dobutamine (Dobutrex)- drug effect | increases cardiac output by increasing contractility (positive inotropy), whic ups SV; similar to dopamine |
| dobutamine (Dobutrex)- uses | heart failure |
| phentolamine (Regitine)- general class | adrenergic-blocking |
| phentolamine (Regitine)- alpha1/2/nonspecific | alpha blocker |
| phentolamine (Regitine)- drug effect | reduces peripheral vascular resistance |
| phentolamine (Regitine)- uses | hypertension, pheochromocytoma, extravasation of vasopressors |
| phentolamine (Regitine)- SE | those who have had an MI, coronary artery disease |
| prazosin (Minipress)- alpha1/2/nonspecific | alpha1-adrenergic blocker |
| prazosin (Minipress)- drug effect | relaxes & dilates the vasculature and smooth muscle around the prostate |
| prazosin (Minipress)- uses | hypertension, urinary obstruction in men w/ BPH |
| prazosin (Minipress)- SE | dramatically lowers BP, orthostatic hypotension |
| metaprolol (Lopressor)- general class | adrenergic-blocking |
| metaprolol (Lopressor)- alpha/beta/1/2 | beta1-blocker |
| metaprolol (Lopressor)- uses | post-MI, hypertension, early MI |
| propranolol (Inderal)- general category | adrenergic-blocking |
| propranolol (Inderal)- alpha/beta | nonselective beta1 and beta2 blocker |
| propranolol (Inderal)- uses | angina, hypertension, dysrhythmias, post-MI, migraine, tremor, pheochromocytoma |
| propranolol (Inderal)- SE | bronchial asthma, bradycardia, Raynaud's disease |
| sotalol (Betapace)- general class | adrenergic-blocking |
| sotalol (Betapace)- alpha/beta | nonselective beta blocker |
| sotalol (Betapace)- uses | difficult-to-treat dysrhythmias |