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Med Surg HIV/AIDS
Med Surg Final
| Question | Answer |
|---|---|
| Functions of the immune system | Protection from outside microroganism, internal threats, and removes damaged cells |
| Responsible for inmmune response | T lymphocytes B lymphocytes |
| B lymphocytes | dormant until antigen enters the body, then multiply and are available for defense |
| T lymphocytes | Rsponsible for rejection of transplanted tissue |
| Humoral response | inmediate, protects against acute, repidly developing bacteria and viruses |
| Cellular response | delayed hypersensitivity, , slow developing bacteria, autoinmune response, allergic reaction, rejections of foreing cells |
| Natural Inmunity | innate, present at birth |
| Aquired Inmunity | received passively from mother's antibodies, animal serum, or antibodies in response to a disease |
| Active aquired inmmunity | Immunization |
| AIDS | Infectious disease characterized by severe deficit in cellular function, caused by HIV |
| AIDS Clinical manifestation | Oportunistic infections and unusual neoplasm, may not appear until late in the infection |
| AIDS related complex | similr to AIDS, can lead to AIDS, and it characterized by 2 or more symptoms/lab related to immunodeficiency |
| AIDS High risk | Male Homosexual, bisexual, IV drug use, Blood transfusion Pt, frequent exposure to blood/body fluids, hetrosexual contact with high risk individual, babies born to infected mothers |
| AIDS Assessment | Malaise, weight loss, Lymphadenopathy at least 3 months, leukopenia, diarrhea,fatigue, night sweats, opportunistic infections |
| Common opportunistic infections in AIDS | Pneumocystis Carinee pneumonia, Kaposi's sarcoma, Fungal infections, candidiasis, cytomegalovirus. |
| Kaposis sarcoma-AIDS opportunistic infection | purplish/red lesions of internal organs and skin |
| HIV transmission | Sexual exposure to genital secretionsParenteral exposure to infected bloodPerinatal exposure to infant trough birth/breast feeding |
| HIV Diagnostic tests | Elisa, western blot, IFA |
| Diagnosis of HIV | 2 test of the same blood sample must be reactive to ELISA, confirmation with Wester Blot or IFA |
| +ELISA -WESTERN | Shold not be considered negative, repeat test 3-6months |
| CD4+T cell count | Monitors progression of HIV, CD4+T decreases as infection progresses |
| CD4+T Normal limits | 500-1600cells/ul |
| CD4+T in AIDS | 200-499cell/ul immune system problems<200 severe immune problems |
| CD4-CD8 ratio | Monitors progression of HIV2:1 normal, in HIV ratio is low since CD4 < |
| Viral culture | measures amount of reverse transcriptase |
| Viral load | Presence of HIV RNA in clients blood |
| P24 antigen | Quantifies amount of HIV viral core protein in pt's serum, used in children younger than 18months |
| HIV compromises | cellular and humeral inmmunities |
| Horizontal transmission of HIV | sexual contact, exposure o blood, body fluids containig blood |
| Vertical Transmission of HIV | Pregnant women infects her fetus |