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Chapter 7:1 A&P
Question | Answer |
---|---|
What is another name for osteoprogenitor cells? | stem cells |
Where are they located? | Endosteum, Periosteum, and Central Canal |
What do osteoblasts synthesize? | Organic matter |
What do osteoblasts mature into? | Osteocytes |
Where do Osteoblasts live? | Lacunae |
What do Osteoblasts control? | Blood concentration of Calcium and Phosphate |
What do Osteoblasts sense on bones? | Stress |
Where do Osteoblasts develop? | Red bone marrow |
What is an Osteoid? | Semi- solid ground substance |
Are Osteoclasts small or large? | Large |
How many nuclei can Osteoclasts contain? | Up to 50 nuclei |
What does organic matter allow for? | Tensile strength |
How much of the matrix is organic matter? | 1/3 |
What is organic matter synthesized by? | Osteoblasts |
What makes up organic matter? | GAGS, proteoglycans, and collagen |
How much of the matrix is inorganic matter? | 2/3 |
What does inorganic matter allow for? | Compressional strength |
What does organic matter provide? | Flexibility |
Without enough inorganic matter, what happens? | Bones become soft, Rickets (Calcium and Vit. D deficiency) |
Without enough organic matter, what happens? | Bones become brittle, Osteogenisus Imperfecta |
What do osteoblasts secrete? | Osteoids |
During bone matrix formation, what deposits into the bone matrix? | Hydroxyapatite Crystals |
What ions precipitate out? | Calcium and Phosphate |
What do the crystals form around? | Collagen fibers |
What are the basic nutrients of bone matrix? | Vit D, Vit C, Calcium, Phosphate, Collagen/Protein |
During bone reabsorption, what releases into the extracellular space next to bone? | Enzymes |
Where are proteolytic enzymes released from? | Lysosomes |
What do the proteolytic enzymes digest? | Collagen fibers |
What does HCl dissolve? | mineral parts |
What frees up and enters the blood? | Calcium and Phosphate |
Where in spongy bones/long bones is bone marrow? | Trabeculae |
Where is red marrow located? | Skull, Pelvis, Vertebrae, Sternum, Ribs |
What is an autologus bone marrow transplant? | Self-Transplant |
What is inorganic matter composed of? | Calcium, Phosphate Salt |
What does inorganic matter provide? | Strength |
What is an allogenic bone marrow transplant? | Transplant with someone else |