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Path- Eponyms T4-2
Leukemia, Lymphoma
Question | Answer |
---|---|
Hairy and T ALL | male preponderance in CA |
HCL, CLL | Not caused by Radiation |
t9;22 | CML Ph chr, som ALL |
t15;17 | Promyel AML M3, RARa, ATRA, DIC |
t8;21 | AML favorable |
t8;14 | B-ALL/Burkitt c-myc |
t12;21 | ALL |
t4;11 | ALL unfavorable |
Acute | 20% Blasts, B sx |
MPO+ | myeloid |
Esterase+ | monocytic |
Auer rods | AML |
Splenomegaly | CML |
abl-bcr t9;22 | Tyrosine kinase |
>4000 periph Lcyte | CLL, SLL |
+Coombs, hypogammaglobulinemia | CLL |
Richter's transformation | Large cell, CLL |
M:F 4:1 | HCL |
Pancytopenia | HCL |
CD 103, CD22, TRAP+ | HCL |
blast count, ringed sideroblast, inc blasts<20% | MDS |
inc RBC, plethora, pruritis | Polycythemia Vera |
anemia, teardrop cell, marrow fibrosis | Chronic Idiopathic myelofibrosis-> AML rarely |
Lymphocytosis | viral infection |
Leukemoid rxn | inc WBC ob infection, chemotx |