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USMLE drug Rxns

QuestionAnswer
TCA Atropine like side effects
Cocaine coronary vasospasm
sumatriptan coronary vasospasm
Doxorubicine/danurubicin dilated cardiomyopathy
Class III soltalol Torsades de pointes
Class Ia (quinidine) Torsades de pointes
antiarrythmics torsades de pointe
cisapride torsades de pointe
clozapine agranulocytosis
carbamezepine agranulocytosis
colchinine agranulocytosis
propythiouracil aplastic anemia, agranulocytosis
methimazole aplastic anemia, agranulocytosis
Methyldopa direct-Cooms positive hemolytic anemia
Chloramphenicol gray baby syndrome
Hemolysis in G6PD deficiency hemolysis IS PAIN (INH, sulfonamides, primaquine, aspirin, Ibuprofen, Nitrofuratoin)
OCPs thrombotic complications
Cough Ace inhibitors
megablastic anemia PMS is a blast (phenytoin, Methotrexate, sulfa drugs)
bleomycin pulmonary fibrosis
busulfan pulmonary fibrosis
amiodarone pulmonary fibrosis, photosensitivity
Macrolides acute choletstatic hepatitis
Halothane focal-massive hepatic necrosis
valproic acid focal-massive hepatic necrosis
acetominophen focal-massive hepatic necrosis
amanita phalloides focal-massive hepatic necrosis
INH Hepatisi, hemolysis in 6GPD
Gynecomastia Some Drugs Create Awesome Knockers (Spirinolactone, digitalis, cimetidine, alcohol abuse, estrogens, ketoconazole)
Clomiphene hot flashes, (also tamoxifen)
Phenytoin gingival hyperplasia, megablastic anemia, Steven Johnson
furosemide gout
heparin osteoperosis
thiazides gout
corticosteroids osteoperosis
Photosensitivity SAT for a photo Sulfonamides, amiodarone, tetracycline
Rash (Steven-Johnson) Ethosuximide, lamotrigine, carbamazepine, phenobarbital, phenytoin, sulfa drugs, penicillin, allopurinol
Created by: ddecampo