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USMLE Antidotes

Toxinantidote/treatmentdescription
Salicylates NaHCO3 (alkalinize)
Amphetamine NH4Cl (acidfy urine) Hypervigilant, paranoid
Anticholinesterase Atropine, pralidoxime
Antimuscarinic, anticholinergic physostigmine salicylate
Beta blockers Glucagon, dopamine, isoproteronal etc bradycardia, 3rd degree block (P and QRS complexes different)
Digitalis normalize K, lidocaine, anti-dig Fab fragments, Mg
Iron Deferoxamine Acute gastric bleeding, metabolic acidosis, scarring leading to GI obstrcution, peroxidation of membrane lipids
Copper Succimer
Arsenic Dimercaporal, succimer, pencillamine
Gold Dimercaporal, succimer, pencillamine
Methemoglobin Methylene blue, vitamin C
cyanide Nitrite, hydroxocobalamin
Carbon monoxide 100 O2, hyperbaric O2
Methanol, ethylene glycol ethanol, dialysis, fomepizole
Opiods naloxone/naltrexone
Benzodiazepines Flumazenil
TCAs NaHCO3 (serum alkalinization)
Heparin protamine
Warfarin Vitamin K, fresh plasma
tPA, streptokinase Aminocaproic acid
Theophylline beta blocker
Lead Dimercaprol, succimer for kids lines on gingivae,lines on epiphyses, encephalopathy, erythrocyte basophilic stippling, abdominal colic, sideroblastic anemia, drops (feet/wrist),
Mercury Dimercaprol (BAL)
Created by: ddecampo
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