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Body System I
Pharmacy Tech Starred and Trade Generic Drug Names
| Generic/Brand | Starred Brand | Classes, Indication, Contra-In |
|---|---|---|
| *chlorpheniramine -OTC | ChlorTrimeton | antihistamine -Tx: allergic rhinitis, urticaria (hives), pruritus (dermatitis), Ax conjunctiva, Ax (give with EPI if severe) -H1 antagonist -caution: dryout easily, drowsiness. Contraindication: taking MAOIs |
| brompheniramine (in Dimetapp)-OTC | antihistamine -Tx: allergic rhinitis, urticaria (hives), pruritus (dermatitis), Ax conjunctiva, Ax (give with EPI if severe) -H1 antagonist | |
| clemastine (Tavist)-OTC | antihistamine -Tx: allergic rhinitis, urticaria (hives), pruritus (dermatitis), Ax conjunctiva, Ax (give with EPI if severe) -H1 antagonist | |
| azelastine (Astelin, Astepro) nasal spray | antihistamine -Tx: allergic rhinitis, urticaria (hives), pruritus (dermatitis), Ax conjunctiva, Ax (give with EPI if severe) -H1 antagonist-sedating | |
| olopatadine (Patanase) nasal spray | antihistamine -Tx: allergic rhinitis, urticaria (hives), pruritus (dermatitis), Ax conjunctiva, Ax (give with EPI if severe) -H1 antagonist | |
| *promethazine | Phenergan | antihistamine -Tx: allergic rhinitis, urticaria (hives), pruritus (dermatitis), Ax conjunctiva, Ax (give with EPI if severe) -H1 antagonist -also used as an anti-emetic |
| cyproheptadine (Periactin) | antihistamine -Tx: allergic rhinitis, urticaria (hives), pruritus (dermatitis), Ax conjunctiva, Ax (give with EPI if severe) -H1 antagonist -also used as weekend migraines | |
| *loratadine -OTC | Claritin, Alavert, Tarvist ND, Dimetapp ND, in Claritin-D | antihistamine -Tx: allergic rhinitis, urticaria (hives), pruritus (dermatitis), Ax conjunctiva, Ax (give with EPI if severe),-H1 antagonist -2nd generation |
| desloratadine (Clarinex, in Clarinex-D) | antihistamine -Tx: allergic rhinitis, urticaria (hives), pruritus (dermatitis), Ax conjunctiva, Ax (give with EPI if severe),-H1 antagonist -2nd generation | |
| cetirizine (Zyrtec, in Zyrtec-D) -OTC | antihistamine -Tx: allergic rhinitis, urticaria (hives), pruritus (dermatitis), Ax conjunctiva, Ax (give with EPI if severe),-H1 antagonist -2nd generation | |
| levocetirizine (Xyzal) | antihistamine -Tx: allergic rhinitis, urticaria (hives), pruritus (dermatitis), Ax conjunctiva, Ax (give with EPI if severe),-H1 antagonist -2nd generation | |
| fexofenidine (Allegra, in Allegra-D) | antihistamine -Tx: allergic rhinitis, urticaria (hives), pruritus (dermatitis), Ax conjunctiva, Ax (give with EPI if severe), -H1 antagonist -2nd generation | |
| *beclomethasone | QVAR -Inhaler; Beconase AQ -Intranasal | Steroid, Tx severe Ax rhinitis that is uncontrolled by antihistamines |
| *dexamethasone | (1)Dexacort Respihaler -Inhaler; Dexacort Turbinaire -Intranasal); (2) Decadron, Hexadron) | Steroid, (1)Tx severe Ax rhinitis that is uncontrolled by antihistamines; (2) Also, Tx of arthritis |
| *triamcinolone (1)Azmacort -Inhaler; Nasacort -Intranasal | (2) Aristocort, Kenalog | Steroid, (1)Tx severe Ax rhinitis that is uncontrolled by antihistamines; (2) Also, Tx of arthritis |
| flunisolide (Aerobid -Inhaler; Nasalide -Intranasal) | Steroid, Tx severe Ax rhinitis that is uncontrolled by antihistamines | |
| budesonide (Pulmicort with formoterol in Symbicort -Inhaler; Rhinocort -Intranasal) | Steroid, Tx severe Ax rhinitis that is uncontrolled by antihistamines | |
| *fluticason | Flovent with salmeterol in Advair -Inhaler; Flonase, Veramyst -Intranasal | Steroid, Tx severe Ax rhinitis that is uncontrolled by antihistamines |
| mometasone (Asmanex -Inhaler; Nasonex -Intranasal) | Steroid, Tx severe Ax rhinitis that is uncontrolled by antihistamines | |
| ciclesonide (Alvesco -Inhaler; Omnaris -Intranasal) | Steroid, Tx severe Ax rhinitis that is uncontrolled by antihistamines | |
| *pseudoephedrine | Sudafed; in Claritin-D; Clarinex-D; Allegra-D; Zyrtec-D) Note: D stands for decongestion and is a combined form | Nasal deco-vasoconstrictor of airway to thicken mucus, indirectly help with coughngestants -vasoconstrictor of airway to thicken mucus, indirectly help with cough (side effects: stimulate alpha-1, beta-1, beta-2, CNS) |
| *phenylephrine | NeoSynephrine -Spray; Sudafed PE -PO; in Actifed; 10% ophthalmic exams: mydriasis | Nasal decongestants -vasoconstrictor of airway to thicken mucus, indirectly help with cough (Side effect: pure alpha-1 stimulant) -Risks: Rebound Congestion, tachyphylaxis, addiction |
| naphazonline (Privine) -topical OTC | Nasal decongestants | |
| tetrahydrozoline (Visine) -Topical OTC | Nasal decongestants | |
| oxymetazonline (Afrin; Dristan; ect) -topical OTC | Nasal decongestants | |
| acetylcysteine (Mucomyst -inhalation soln in IPPB; Acetadote IV -APAP OD) | mucolytics | |
| dornase alfa (Pulmozyme) | mucolytics -Tx cystic fibrosis | |
| *guaifenesin | Robitussin; Mucinex -Tablet; Humibid E; "GG" | expectorant |
| iodides (SSKI) -in combination OTCs: ammonium; ipecac -vomit inducer | expectorant | |
| codine (in combination: C-V; Note: codine by itself is C-II) | antitussives | |
| sildenafil (Viagra) | Erectile Dysfunction (ED), Contraindications: nitrate | |
| vardenafil (Levitra) | Erectile Dysfunction (ED), Contraindications: nitrate | |
| tadalafil (Cialis) | Erectile Dysfunction (ED), Contraindications: nitrate; faster onset, longer duration aka:"Weekender" | |
| finasteride (Proscar, Propecia) | testosterone blockers: Tx BPH, longer onset (takes months) | |
| dutasteride (Avodart) | testosterone blockers: Tx BPH, longer onset (takes months) | |
| *terazosin | Hytrin | alpha-1 blockers: Tx BPH and HTN, fast acting, reduces BP causing "Orthostatic hypotension" -take at night to reduce this side effect. |
| *doxazoxin | Cardura | alpha-1 blockers: Tx BPH and HTN, fast acting, reduces BP causing "Orthostatic hypotension" -take at night to reduce this side effect. |
| tamsulosin (Flomax) | alpha-1 blockers: Tx BPH, fast acting, reduces BP causing "Orthostatic hypotension" -take at night to reduce this side effect. | |
| alfuzosin (Uroxatral) | alpha-1 blockers: Tx BPH, fast acting, reduces BP causing "Orthostatic hypotension" -take at night to reduce this side effect. | |
| silodosin (Rapaflo) | alpha-1 blockers: Tx BPH, fast acting, reduces BP causing "Orthostatic hypotension" -take at night to reduce this side effect. | |
| epinephrine | Adrenalin, Epi-Pen -autoinjector for anaphylaxis | bronchodilater-strong sympathomimetic (alpha -1, beta-1 and beta-2 agonist), tx: asthma, emphysia, chronic bronchitis, allergic reactions, DOC for anaphylaxis, status asthmaticus |
| *metaproterenol | Alupent | bronchodilater-sympathomimetic (selective beta-2 agonist), tx: asthma, emphysema, chronic bronchitis, allergic reactions |
| *terbutaline | Brethine -PO dose = 10x SQ dose | bronchodilater-sympathomimetic (selective beta-2 agonist), tx: asthma, emphysema, chronic bronchitis, allergic reactions |
| *albuterol | Proventil HFA, Ventolin, Volmax (with ipratropium in Combivent, DuoNeb) | bronchodilater-sympathomimetic (selective beta-2 agonist), tx: asthma, emphysema, chronic bronchitis, allergic reactions |
| levalbuterol (Xopenex) | bronchodilater-sympathomimetic (selective beta-2 agonist), tx: asthma, emphysema, chronic bronchitis, allergic reactions -short acting | |
| pirbuterol (Maxair) | bronchodilater-sympathomimetic (selective beta-2 agonist), tx: asthma, emphysema, chronic bronchitis, allergic reactions -Short acting | |
| *salmeterol | Serevent (with fluticasone in Advair) | bronchodilater-sympathomimetic (selective beta-2 agonist), tx: asthma, emphysema, chronic bronchitis, allergic reactions -long active for noturnal sx, not for rescue situations. |
| formoterol (Foradil, Perforomist) w/ budesonide in Symbicort | bronchodilater-sympathomimetic (selective beta-2 agonist), tx: asthma, emphysema, chronic bronchitis, allergic reactions -long acting | |
| arformoterol (Brovana) | bronchodilater-sympathomimetic (selective beta-2 agonist), tx: asthma, emphysema, chronic bronchitis, allergic reactions | |
| theophylline (Elixophyllin, Uniphyl) | bronchodilator- xanthine (caffeine -relaxes airway smooth muscle, but also affect cardiac and CNS, also causes diuresis and increased gastric secretion -ulcergenics) -Tx: acute asthma, maintenance -PO | |
| aminophylline | bronchodilator- xanthine (caffeine -relaxes airway smooth muscle, but also affect cardiac and CNS, also causes diuresis and increased gastric secretion -ulcergenics) -Tx: acute asthma, maintenance -IV | |
| *ipratropium bromide | Atrovent (with albuterol in Combivent, DuoNeb) | bronchodilator -anticholinergic -prevent bronchoconstriction; Tx: emphysema, chronic bronchitis |
| tiotropium (Spiriva) | bronchodilator -anticholinergic -prevent bronchoconstriction; Tx: emphysema, chronic bronchitis | |
| zafirflukast (Accolate) | Leukotriene antagonist/modifier -prevention of asthma | |
| montelukast (Singular) | Leukotriene antagonist/modifier -prevention of asthma | |
| zileuton (Zyflo, Zyflo CR) | Leukotriene antagonist/modifier -prevention of asthma | |
| *cromolyn sodium | *Nasalcrom, Intal, Gastrocrom, Opticrom | Mast Cell stabilizers -Prevention of asthma |
| nedocromil (Tilade inhaler, Alocril -ophthalmic) | Mast Cell stabilizers -Prevention of asthma | |
| lodosamide (Alomide -ophthmalmic only) | Mast Cell stabilizers -Prevention of asthma | |
| omalizumab (Xolair) | IgE inhibitor -Prevention of asthma | |
| hydrocodone (Hycodan, in Tussionex)_C-III | Antitussive | |
| *dextromethorphan | DM, Delsym -OTC | Antitussive |
| calcitonin (Miacalcin) | tx osteoporosis | |
| raloxifene (Evista) | tx osteoporosis -selective estrogen receptor modulator | |
| eteriparatide (Forteo) | tx osteoporosis -human parathyroid hormone | |
| estrogen | tx osteoporosis -hormone replacement therapy | |
| alendronate (Fosamax) | tx osteoporosis -once/day | |
| risedronate (Actonel) biphosphate | tx osteoporosis -twice/wk | |
| tidronate (Didronel) | tx osteoporosis -first in class developed for Paget's dz | |
| ibandronate (Boniva) | tx osteoporosis -once/month | |
| zoledronic acid (Reclast) | tx osteoporosis -1/yr (IV infusion) | |
| asprin -ASA (Bufferin Ecotrin) | NSAIDs (Salicylate) -1st line Tx of Arthritis, stroke | |
| diflunisal (Dolobid) | NSAIDs (Salicylate) -1st line Tx of Arthritis | |
| salsalate (Disalcid) | NSAIDs (Salicylate) -1st line Tx of Arthritis | |
| *ibuprofen | Motrin, NeoProfen IV -OTC brands: Advil, Motrin IB | NSAIDs -1st line Tx of Arthritis |
| fenoprofen (Nalfon) | NSAIDs -1st line Tx of Arthritis | |
| ketoprofen (Oruvail) -OTC brand: Orudis KT | NSAIDs -1st line Tx of Arthritis | |
| flurbiprofen (Ansaid) | NSAIDs -1st line Tx of Arthritis | |
| *naproxen | Naprosyn -OTC brand: *Aleve | NSAIDs -1st line Tx of Arthritis |
| tolmetin (Tolectin) | NSAIDs -1st line Tx of Arthritis | |
| meclofenamate (Meclomen) | NSAIDs -1st line Tx of Arthritis/causes severe diarrhea | |
| *piroxicam | Feldene | NSAIDs -1st line Tx of Arthritis |
| *sulindac | Clinoril | NSAIDs -1st line Tx of Arthritis |
| *diclofenac Na | Voltaren, Voltaren gel* -diclofenac sodium + misoprostol = Arthrotec | NSAIDs -1st line Tx of Arthritis |
| diclofenac K (Cataflam); diclofenac patch (Flector) | NSAIDs -1st line Tx of Arthritis | |
| etodolac (Lodine) | NSAIDs -1st line Tx of Arthritis | |
| *ketorolac | Toradol -IM form available | NSAIDs -1st line Tx of Arthritis (more ulcergenic than other NSAIDs use max 5 days) |
| nabumetone (Relafen) | NSAIDs -1st line Tx of Arthritis (QD -less toxic to stomach) | |
| oxaprozin (Daypro) | NSAIDs -1st line Tx of Arthritis (QD -less toxic to stomach) | |
| meloxicam (Mobic) | NSAIDs -1st line Tx of Arthritis | |
| indomethacin (indocin, Indocin SR) | NSAIDs -1st line Tx of Arthritis/ for PDA | |
| *celecoxib | Celebrex | NSAIDs (COX 2 inhibitor) -1st line Tx of Arthritis |
| rofecoxib (Vioxx) | NSAIDs (COX 2 inhibitor) -1st line Tx of Arthritis -off market | |
| valdecoxib (Bextra) | NSAIDs (COX 2 inhibitor) -1st line Tx of Arthritis -off market | |
| *hydrocortisone | HC -(Cortef, Solu-Cortef) | CorticoSteroid -2nd line Tx of Arthritis |
| prednisone (Deltasone) | CorticoSteroid -2nd line Tx of Arthritis | |
| prednisolone (Orapred, Orapred ODT, Pedia-Pred, Prelone, Flo-Pred, Millipred, Veripred 20) | CorticoSteroid -2nd line Tx of Arthritis | |
| betametasone (Celestone, Celestone SoluSpan) | CorticoSteroid -2nd line Tx of Arthritis | |
| *methylprednisolone | Medrol, Solu-Medrol, Depo-Medrol | CorticoSteroid -2nd line Tx of Arthritis |
| *sulfamethosazole/trimethoprim | Bactrim, Septra | urinary antibacterials -tx UTI, might form crystals in urine, so drink plenty of water |
| *ciprofloxacin | Cipro -fluoroquinolones | urinary antibacterials -tx UTI, broad spectrum (causes resistance) |
| *epoetin alfa | Epo (Epogen, Procrit) | hematopoietics -Tx anemia of renal failure |
| darbepoetin (Aranesp) | hematopoietics -Tx anemia of renal failure | |
| *oxybutynin | Ditropan | anti-muscarinics -Tx incontinence "over-active bladder" |
| tolterodine (Detrol) | anti-muscarinics -Tx incontinence "over-active bladder" | |
| darifenacin (Enablex) | anti-muscarinics -Tx incontinence "over-active bladder" | |
| trospium (Sanctura) | anti-muscarinics -Tx incontinence "over-active bladder" | |
| solifenacin (Vesicare) | anti-muscarinics -Tx incontinence "over-active bladder" | |
| fesoterodine fumarate (Toviaz) | anti-muscarinics -Tx incontinence "over-active bladder" | |
| *bethanechol | Urecholine | cholinergics -Tx urine retention |
| *imipramine | Tofranil | enuretics -tx "bed wet"; for kids/not for adults |
| desmopressin (DDAVP) | enuretics -tx "bed wet" and diabetes insipidus | |
| lypressin (Diapid) | enuretics -tx "bed wet" and diabetes insipidus | |
| *phenazopyrindine | Pyridium | urinary analgesics -Tx the pain of urinary infection; DISCOLOR URINE TO ORANGE RED/DOES NOT CURE INFECTION |
| morphine | narcotic analgesics -Tx the pain of nephrolithiasis | |
| meperidine (Demerol) | narcotic analgesics -Tx the pain of nephrolithiasis | |
| *hydromorphone | Dilaudid | narcotic analgesics -Tx the pain of nephrolithiasis |
| aliskiren (Tekturna) | Direct renin inhibitor -Tx: HTN -expensive, 1st in class, PO/Rx | |
| vasopressin | endogenous ADH -Tx diabetes insipidus | |
| acetazolamide (Diamox) -PO | diurectics -Tx: glaucoma -carbonic anhydrase inhibitor | |
| *hydrochlorothiazide | HCTZ, HydroDiuril, Oretic -PO | diuretics (thiazide) -Tx: HTN -prefer & edema by causing diuresis; MOA: blocks Na+ (with K+ & Cl- through cotransporter) in the renal tubules; Side Effects: hypokalemia, hypomagnesemia, hyperglycemia, hyperuricemia |
| chlorthalidone (Hygroton) -PO | diuretics (thiazide-like) -Tx: HTN -prefer & edema by causing diuresis; MOA: blocks Na+ (with K+ & Cl- through cotransporter) in the renal tubules; Side Effects: hypokalemia, hypomagnesemia, hyperglycemia, hyperuricemia | |
| indapamide (Lozol) -PO | diuretics (thiazide-like) -Tx: HTN -prefer & edema by causing diuresis; MOA: blocks Na+ (with K+ & Cl- through cotransporter) in the renal tubules; Side Effects: hypokalemia, hypomagnesemia, hyperglycemia, hyperuricemia | |
| metolazone (Diulo, Zaroxolyn) -PO | diuretics (thiazide-like) -Tx: HTN -prefer & edema by causing diuresis; MOA: blocks Na+ (with K+ & Cl- through cotransporter) in the renal tubules; Side Effects: hypokalemia, hypomagnesemia, hyperglycemia, hyperuricemia | |
| *furosemide | Lasix -PO/IV | loop diurectic (most potent) -Tx: severe edema and CHF; s. effects: severe hypokalemia, dehydration, ototoxity (c.n VIII damage) -anacusis (hearing loss)/vertigo (vestibular damage); MOA: blocks electrolyte reabsorption in Loop of Henle |
| ethacrynic acid (Edecrin)-PO/IV | loop diurectic (most potent) -Tx: severe edema and CHF; s. effects: severe hypokalemia, dehydration, ototoxity (c.n VIII damage) -anacusis (hearing loss)/vertigo (vestibular damage); MOA: blocks electrolyte reabsorption in Loop of Henle | |
| bumetanide (Bumex) -PO/IV | loop diurectic (most potent) -Tx: severe edema and CHF; s. effects: severe hypokalemia, dehydration, ototoxity (c.n VIII damage) -anacusis (hearing loss)/vertigo (vestibular damage); MOA: blocks electrolyte reabsorption in Loop of Henle | |
| torsemide (Demadex) -PO/IV | loop diurectic (most potent) -Tx: severe edema and CHF; s. effects: severe hypokalemia, dehydration, ototoxity (c.n VIII damage) -anacusis (hearing loss)/vertigo (vestibular damage); MOA: blocks electrolyte reabsorption in Loop of Henle | |
| *spironolactone | Aldactone, in Aldactazide | K-sparing diuretic (weak/combine w/ other diurectics to counteract hypokalemia) -Tx: HTN, edema; s. effects: hyperkalemia, gynecomastia; MOA: blocks Na+/K+ exchange in the distal tubule (loss of Na+ and Water, conserve K+) -Aldosterone antagonist |
| *triamterene | Dyrenium, in *Dyazide | K-sparing diuretic (weak/combine w/ other diurectics to counteract hypokalemia) -Tx: HTN, edema; s. effects: hyperkalemia, gynecomastia; MOA: blocks Na+/K+ exchange in the distal tubule (loss of Na+ and Water, conserve K+) |
| amilorde (Midamor, in Moduretic) | K-sparing diuretic (weak/combine w/ other diurectics to counteract hypokalemia) -Tx: HTN, edema; s. effects: hyperkalemia, gynecomastia; MOA: blocks Na+/K+ exchange in the distal tubule (loss of Na+ and Water, conserve K+) | |
| eplerenone (Inspra) | K-sparing diuretic (weak/combine w/ other diurectics to counteract hypokalemia) -Tx: HTN, edema; s. effects: hyperkalemia, gynecomastia; MOA: blocks Na+/K+ exchange in the distal tubule (loss of Na+ and Water, conserve K+) | |
| spironolactone + HCTZ (Aldactazide) | Combined diuretics | |
| *triamterene + HCTZ (Maxzide) | Dyazide | Combined diuretics |
| amiloride + HCTZ (Moduretic) | Combined diuretics | |
| Manitol and Urea -IV | osmotic diuretics -Tx: cerebral edema (ICP-intrancranial press) & drugs OD (force diuresis). MOA: large mole can't be reabsorbed after filtered, but has osmotic pulls for H20. Cautions: temp incr plasma vol; may aggravate CHF, PE(pulm edema) | |
| glycerin -PO | osmotic diuretics -Tx: glaucoma (decr IOP). MOA: large mole can't be reabsorbed after filtered, but has osmotic pulls for H20. Cautions: temp incr plasma vol; may aggravate CHF, PE(pulm edema) | |
| *captopril | Capoten | ACE inhibitor -Tx: HTN, Delay CHF (prevnt: diabetic nephropathy, stroke, migraines, off label: SL for HTN crisis); MOA: bocks angiotensin coverting enz. -ContraI: pregnancy -take empty stomach -S effects: 1st dose effects, persistent dry cough -old drug |
| *enalapril | Vasotec, in Vaseretic, Teczem, Lexxel (enalaprilat -Vasotec IV) | ACE inhibitor -Tx: HTN, Delay CHF (prevnt: diabetic nephropathy, stroke, migraines); MOA: bocks angiotensin coverting enz. -ContraI: pregnancy -S effects: 1st dose effects, persistent dry cough -old drug |
| *lisinopril | Zestril, Prinivil; in Zestoretic, Prinzide | ACE inhibitor -Tx: HTN, Delay CHF (prevnt: diabetic nephropathy, stroke, migraines); MOA: bocks angiotensin coverting enz. -ContraI: pregnancy -S effects: 1st dose effects, persistent dry cough -old drug |
| *benazepril | Lotensin; in Lotrel with amlodipine | ACE inhibitor -Tx: HTN, Delay CHF (prevnt: diabetic nephropathy, stroke, migraines); MOA: bocks angiotensin coverting enz. -ContraI: pregnancy -S effects: 1st dose effects, persistent dry cough -old drug |
| ramipril (Altace) | ACE inhibitor -Tx: HTN, Delay CHF (prevnt: diabetic nephropathy, stroke, migraines); MOA: bocks angiotensin coverting enz. -ContraI: pregnancy -Take empty stomach -S effects: 1st dose effects, persistent dry cough | |
| fosinopril (Monopril) | ACE inhibitor -Tx: HTN, Delay CHF (prevnt: diabetic nephropathy, stroke, migraines); MOA: bocks angiotensin coverting enz. -ContraI: pregnancy -S effects: 1st dose effects, persistent dry cough | |
| quinapril (Accupril) | ACE inhibitor -Tx: HTN, Delay CHF (prevnt: diabetic nephropathy, stroke, migraines); MOA: bocks angiotensin coverting enz. -ContraI: pregnancy -Take empty stomach -S effects: 1st dose effects, persistent dry cough | |
| spirapril (Renormax) | ACE inhibitor -Tx: HTN, Delay CHF (prevnt: diabetic nephropathy, stroke, migraines); MOA: bocks angiotensin coverting enz. -ContraI: pregnancy -S effects: 1st dose effects, persistent dry cough | |
| moexipril (Univasc) | ACE inhibitor -Tx: HTN, Delay CHF (prevnt: diabetic nephropathy, stroke, migraines); MOA: bocks angiotensin coverting enz. -ContraI: pregnancy -S effects: 1st dose effects, persistent dry cough | |
| trandolapril (Mavik) | ACE inhibitor -Tx: HTN, Delay CHF (prevnt: diabetic nephropathy, stroke, migraines); MOA: bocks angiotensin coverting enz. -ContraI: pregnancy -S effects: 1st dose effects, persistent dry cough | |
| perindopril (Aceon) | ACE inhibitor -Tx: HTN, Delay CHF (prevnt: diabetic nephropathy, stroke, migraines); MOA: bocks angiotensin coverting enz. -ContraI: pregnancy -S effects: 1st dose effects, persistent dry cough | |
| enalapril + HCTZ (Vaseretic) | combined form -S. effects: persistent dry cough | |
| enalapril + diltiazem (Teczem) | combined form -S. effects: persistent dry cough | |
| enalapril + felodipine (Lexxel) | combined form -S. effects: persistent dry cough | |
| benazepril + amlodipine (Lotrel) | combined form -S. effects: persistent dry cough | |
| losartan (Cozaar) -with amlodipine in Exforge | ARB's -Tx: same as ACE inhibitors, but no s.effects of 1st dose (rapid drop of BP -dizziness/fatigue), persistent dry cough | |
| eprosartan (Teveten) | ARB's -Tx: same as ACE inhibitors, but no s.effects of 1st dose (rapid drop of BP -dizziness/fatigue), persistent dry cough | |
| valsartan (Diovan) -with amlodipine in Exforge | ARB's -Tx: same as ACE inhibitors, but no s.effects of 1st dose (rapid drop of BP -dizziness/fatigue), persistent dry cough | |
| *irbesartan | Avapro | ARB's -Tx: same as ACE inhibitors, but no s.effects of 1st dose (rapid drop of BP -dizziness/fatigue), persistent dry cough |
| candesartan (Atacand) | ARB's -Tx: same as ACE inhibitors, but no s.effects of 1st dose (rapid drop of BP -dizziness/fatigue), persistent dry cough | |
| telmisartan (Micardis) | ARB's -Tx: same as ACE inhibitors, but no s.effects of 1st dose (rapid drop of BP -dizziness/fatigue), persistent dry cough | |
| olmesartan (Benicar) -with amlodipine in Azor | ARB's -Tx: same as ACE inhibitors, but no s.effects of 1st dose (rapid drop of BP -dizziness/fatigue), persistent dry cough | |
| nitroglycerin (NTG) | vasodilators of cardio (nitrate) -Tx: pectoralis angina -SL: acute and exercise-induced;Translingual spray: acute; PO, topical, transdermal: prophylaxis; IV: before surgery -ContraI: ED drugs -wean patients | |
| isosorbide dinitrate | Isordil, Dilatrate-SR, Bidil (with hydralazine) | vasodilators of cardio (nitrate)-Tx: pectoralis angina -SL: acute; PO-SR: prophylaxis -ContraI: ED drugs -wean patient: rebound angina, HTN might develop |
| isosorbide momonitrate (ISMO, Monoket) | vasodilators of cardio (nitrate)-Tx: prophylaxis pectoralis angina ONLY -ContraI: ED drugs -wean patient: rebound angina, HTN might develop | |
| *dipyridamole | Persantine | ?vasodilators of cardio? -Tx: prophylaxis pectoralis angina and more of antiplatelet -reduces strokes |
| *verapamil | Isoptin, Calan, Verelan PM, Covera HS | ca++ channel blockers -Tx: pectoralis angina (PO), arrythmia (SVT)-IV -Class IV, HTN (SR/XL)-wean patient: rebound angina, HTN might develop |
| *nifedipine | Procardia, Adalat | ca++ channel blockers -Tx: pectoralis angina (PO), arrythmia (SVT)-IV, HTN (SR/XL)-wean patient: rebound angina, HTN might develop |
| *diltiazem | Cardizem, Cardizem SR, Cardizem CD, Cardizem LA, Dilacor XR, Tiazac, Teczem (with enalapril) | ca++ channel blockers -Tx: pectoralis angina (PO), arrythmia (SVT)-IV -Class IV, HTN (SR/XL)-wean patient: rebound angina, HTN might develop |
| *amlodipine | Norvasc, Lotrel w/ benazepril, CADuet w/ atoravastatin, Exforge w/ valsartan, Azor w/ olmesartan | ca++ channel blockers -Tx: pectoralis angina (PO), arrythmia (SVT)-IV, HTN (SR/XL)-wean patient: rebound angina, HTN might develop |
| bepridil (Vascor) | ca++ channel blockers -Tx: pectoralis angina (PO), arrythmia (SVT)-IV, HTN (SR/XL)-wean patient: rebound angina, HTN might develop | |
| nicardipine (Cardene) | ca++ channel blockers -Tx: pectoralis angina (PO), arrythmia (SVT)-IV, HTN (SR/XL)-wean patient: rebound angina, HTN might develop | |
| felodipine (Plendil, Lexxel w/ enalapril) | ca++ channel blockers -Tx: pectoralis angina (PO), arrythmia (SVT)-IV, HTN (SR/XL)-wean patient: rebound angina, HTN might develop | |
| isradipine (DynaCirc) | ca++ channel blockers -Tx: pectoralis angina (PO), arrythmia (SVT)-IV, HTN (SR/XL)-wean patient: rebound angina, HTN might develop | |
| nisoldipine (Sular) | ca++ channel blockers -Tx: pectoralis angina (PO), arrythmia (SVT)-IV, HTN (SR/XL)-wean patient: rebound angina, HTN might develop | |
| nimodipine (Nimotop) | ca++ channel blockers -Tx: pectoralis angina (PO), arrythmia (SVT)-IV, HTN (SR/XL), Acute Stroke, Also approved for subarachnoid hemorrhage -may pull from capsule and give via NGT -wean patient: rebound angina, HTN might develop | |
| *propranolol | Inderal, Inderide w/ HCTZ -PO/Inj, Non-selective | beta blockers -Tx: angina pectoralis, Class II arrhythmia -PO/inj, HTN, migraines, glaucoma (decr IOP)-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe |
| *atenolol | Tenormin, Tenoretic w/ chlorthalidone, Cardio-selective | beta blockers -Tx: angina pectoralis, arrhythmia, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe |
| *metoprolol | Lopressor, Toprol XL, Lopressor HCT w/ HCTZ, Cardio-selective | beta blockers -Tx: angina pectoralis, arrhythmia, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe |
| bisoprolol (Zebeta, Ziac w/ HCTZ, Cardio-selective | beta blockers -Tx: angina pectoralis, arrhythmia, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe | |
| carteolol (Cartrol, Ocupress), Non-selective | beta blockers -Tx: angina pectoralis, arrhythmia, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe | |
| nadolol (Corgard, Corzide w/ bendroflumethiazide), Non-selective | beta blockers -Tx: angina pectoralis, arrhythmia, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe | |
| *carvedilol | Coreg, Coreg CR | beta blockers -Tx: angina pectoralis, arrhythmia, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe |
| acebutolol (Sectral), Cardio-selective | beta blockers -Tx: angina pectoralis, arrhythmia, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe | |
| betaxolol (Betoptic, Kerlone), Cardio-selective | beta blockers -Tx: angina pectoralis, arrhythmia, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe | |
| labetalol (Normodyne, Trandate), Non-selective | beta blockers -Tx: angina pectoralis, arrhythmia, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe | |
| penbutolol (Levatol) | beta blockers -Tx: angina pectoralis, arrhythmia, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe | |
| pindolol (Visken) | beta blockers -Tx: angina pectoralis, arrhythmia, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe | |
| timolol (Blocadren, Timoptic, Timolide w/ HCTZ) | beta blockers -Tx: angina pectoralis, arrhythmia, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe | |
| nebivolol (Bystolic) | beta blockers -Tx: angina pectoralis, arrhythmia, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe | |
| sotalol (Betapace) | beta blockers -Tx: angina pectoralis, Class II arrhythmia -PO, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe | |
| esmolol (Brevibloc) | beta blockers -Tx: angina pectoralis, Class II arrhythmia -IV, HTN, migraines, glaucoma (decr IOP))-SE of non-selective beta blocker (hi dose): blocks beta 2, bronchospasm, can't breathe | |
| ranolazine (Ranexa) | miscellaneous antiangina drug -Tx: chronic angina or angina can't be controlled by other antianginal drugs | |
| streptokinase (Streptase) | thrombolytics - Tx: coronary thrombosis (MI), thrombo-embolic stroke (CVA), deep vein thrombosis (DVT), pulmonary embolism (PE), clear IV catheters "flush" -riks: hemorrhage, allergy with recombinant DNA products | |
| alteplase (Activase) -ordered as TPA | thrombolytics - Tx: coronary thrombosis (MI), thrombo-embolic stroke (CVA), deep vein thrombosis (DVT), pulmonary embolism (PE), clear IV catheters "flush" -riks: hemorrhage, allergy with recombinant DNA products | |
| tenecteplase (TKNase) | thrombolytics - Tx: coronary thrombosis (MI), thrombo-embolic stroke (CVA), deep vein thrombosis (DVT), pulmonary embolism (PE), clear IV catheters "flush" -riks: hemorrhage, allergy with recombinant DNA products | |
| reteplase (Retevase) r-PA | thrombolytics - Tx: coronary thrombosis (MI), thrombo-embolic stroke (CVA), deep vein thrombosis (DVT), pulmonary embolism (PE), clear IV catheters "flush" -riks: hemorrhage, allergy with recombinant DNA products | |
| *digoxin | "dig" (Lanoxin, Lanoxicaps, Digitek) | cardiotonics digitalis glycoside -Tx: CHF -stengthens heart beat (+ inotropic) by inhibiting Na/K pump -need apical pulse, digitalis loading -if HR<60, hold a dose -hypokalemia incr. digitalis toxicity (arrhythmogenic, halos/rings of lite arnd obj.) |
| digitalis immune FAB (Digibind, DgiFab) | antidote for digitalis OD | |
| inamrinone | cardiotonics non-digitalis -Tx: short-term CHF -stengthens heart beat (+ inotropic), can also cause vasodilation | |
| milrinone (Primacor) | cardiotonics non-digitalis -Tx: short-term CHF -stengthens heart beat (+ inotropic), can also cause vasodilation | |
| quinidine (Quinidex -83% of quinidine with sulfate, Quinaglute -62% quinidine with gluconate) | anti-arrhythmic drug -Class I: membrane stablizing -indication: convert atrial tachycardia to NSR -caution: paradoxical VAGOLYTIC effect -cinchonism: collection of Sx (tinnitus, hearing loss, vertigo, HA) | |
| *procainamide | Pronestyl | anti-arrhythmic drug -Class I: membrane stablizing -SLE (lupus-like Sx of black furry tongue) |
| *lidocaine | Xylocaine | anti-arrhythmic drug -Class I: membrane stablizing -indication: ectopics/vent. arrhythmia -Inj. has local anesthetic effect e.g DDS, ER; gargle lidocain vicous for mouth/lip pain -don't use with epinephrine/preservatives for IV admin. |
| disopyramide (Norpace) | anti-arrhythmic drug -Class I: membrane stablizing | |
| mexiletine (Mexitil) | anti-arrhythmic drug -Class I: membrane stablizing | |
| tocainide (Tonocard) | anti-arrhythmic drug -Class I: membrane stablizing | |
| flecainide (Tambocor) | anti-arrhythmic drug -Class I: membrane stablizing | |
| propafenone (Rythmol) | anti-arrhythmic drug -Class I: membrane stablizing | |
| amiodarone (Cordarone, Pacerone) | anti-arrhythmic drug -Class III: K-like blocker -if EKG abnormal, divide dose in half | |
| bretylium (Bretylol) | anti-arrhythmic drug -Class III: K-like blocker -if EKG abnormal, divide dose in half | |
| ibutilide (Corvert) | anti-arrhythmic drug -Class III: K-like blocker -if EKG abnormal, divide dose in half | |
| dofetilide (Tikosyn) | anti-arrhythmic drug -Class III: K-like blocker -if EKG abnormal, divide dose in half | |
| adenosine (Adenocard) | anti-arrhythmic drug: miscellaneous -rapid IV bolus only for both arrhythmia and stress test | |
| DOPamine | sympathomimetic -Tx: shock -vasoconstriction of perifpheral blood vessels | |
| DOBUTamine (Dobutrex) | sympathomimetic -Tx: shock -beta-one agonist, incr. CO (little beta-two or vessel effects) | |
| isoproterenol (Isuprel) | sympathomimetic -Tx: shock -beta-one and beta-two agonist, incr. HR | |
| cholestyramine (Questran) | hypolipidemics -bile acid sequestrants (1)incr. cholesterol breakdown -won't remove plaques from vessel walls | |
| colestipol (Colestid) | hypolipidemics -bile acid sequestrants (1)incr. cholesterol breakdown -won't remove plaques from vessel walls | |
| colesevelam (WelChol) | hypolipidemics -bile acid sequestrants (1)incr. cholesterol breakdown -won't remove plaques from vessel walls | |
| ezetimibe (Zetia, w/ simvastatin in Vytorin) | hypolipidemics -(2)prevent cholesterol absorption in intestine -won't remove plaques from vessel walls | |
| lovastatin (Mevacor, Altocor, w/ niacin in Advicor) | hypolipidemics -HMG-CoA reductase inhibitor (3) decrease cholesterol production in liver -won't remove plaques from vessel walls | |
| *pravastatin | Pravachol, w/ ASA in Pravigard PAC | hypolipidemics -HMG-CoA reductase inhibitor (3) decrease cholesterol production in liver -won't remove plaques from vessel walls |
| *simvastatin | Zocor, w/ ezetimibe in Vytorin | hypolipidemics -HMG-CoA reductase inhibitor (3) decrease cholesterol production in liver -won't remove plaques from vessel walls |
| fluvastatin (Lescol) | hypolipidemics -HMG-CoA reductase inhibitor (3) decrease cholesterol production in liver -won't remove plaques from vessel walls | |
| *atorvastatin | Lipitor, w/ amlodipin in CADuet | hypolipidemics -HMG-CoA reductase inhibitor (3) decrease cholesterol production in liver -won't remove plaques from vessel walls |
| rosuvastatin (Crestor) | hypolipidemics -HMG-CoA reductase inhibitor (3) decrease cholesterol production in liver -won't remove plaques from vessel walls | |
| fenofibrate (Tricor), fenofibrate acid (Trilipix) | hypolipidemics -miscellaneous -won't remove plaques from vessel walls | |
| gemfibrozil (Lopid) | hypolipidemics -miscellaneous -won't remove plaques from vessel walls | |
| niacin (NiaSpan, Niacor, Slo-Niacin, extended release, w/ simvastatin in Simcor, w/ lovastatin in Advicor) aka nicotinic acid or Vitamin B-3 | hypolipidemics -miscellaneous -won't remove plaques from vessel walls | |
| *hydralazine | Apresoline, w/isosorbide dinitrate in Bidil | anti-hypertensive vasodilator -Tx: HTN -use w/ (-) chronotropic drug b/c reflex tachycardia may occur -use w/ diuretic b/c reflex incr. renin level ->H20 retetion |
| minoxidil (Loniten) | anti-hypertensive vasodilator -Tx: HTN -use w/ (-) chronotropic drug b/c reflex tachycardia may occur -use w/ diuretic b/c reflex incr. renin level ->H20 retetion -S.E: hypertrichosis (hair overgrowth) | |
| nitroglycerin | anti-hypertensive vasodilator -Tx: HTN -use w/ (-) chronotropic drug b/c reflex tachycardia may occur -use w/ diuretic b/c reflex incr. renin level ->H20 retetion | |
| *1.prazosin, *2.terazosin *3.doxazosin | 1.Minipress, w/ polythiazide in Minizide, 2.Hytrin, 3.Cardura | alpha-1 blocker -Tx: resistant HTN -no relex tachycardia but has 1st dose effects of orthostatic hypotension (take HS, don't drive for 12-24hrs after dose) |
| *methyldopa | Aldomet, w/ HCTZ in Aldoril | alpha-2 agonist -Tx: HTN -work on CNS, stimul. alpha-2 receptors of presynap inhibitory to block release of neurotransmitters. -Causes drowsiness, driving warning, alcohol and other CNS drug warning. -Acts as False NT -reound HTN |
| *clonidine | Catapres, Catapres TTS-transdermal route, w/chlorthalidone in Combipes | alpha-2 agonist -Tx: HTN -work on CNS, stimulate alpha-2 receptors of presynaptic inhibitory to block release of neurotransmitters. -Causes drowsiness, driving warning, alcohol and other CNS drug warning -rebound HTN |
| guanabenz (Wytensin) | alpha-2 agonist -Tx: HTN -work on CNS, stimulate alpha-2 receptors of presynaptic inhibitory to block release of neurotransmitters. -Causes drowsiness, driving warning, alcohol and other CNS drug warning -rebound HTN | |
| guanfacine (Tenex) | alpha-2 agonist -Tx: HTN -work on CNS, stimulate alpha-2 receptors of presynaptic inhibitory to block release of neurotransmitters. -Causes drowsiness, driving warning, alcohol and other CNS drug warning -rebound HTN | |
| nitroprusside (NitroPress) | Hypertensive crisis -Tx: severe HTN -IV infusion -Mix in D5W only, protect from light, short stability time -SE: cyanide toxicity | |
| diazoxide (Hyperstat) | Hypertensive crisis -Tx: severe HTN -rapid IV push -SE: severe hypotension | |
| fenoldopam (Corlopam) | Hypertensive crisis -Tx: severe HTN -IV infusion | |
| ferrous sulfate (FeSO4) -PO | hematopoietic/erythrocyte production -Tx: Fe deficiency anemia -provides more Fe than gluconate in the same dose | |
| ferrous gluconate (Fergon) -PO | hematopoietic/erythrocyte production -Tx: Fe deficiency anemia -provides less Fe than SO4 in the same dose | |
| iron dextran (Dexferrium) -IM/IV | hematopoietic/erythrocyte production -Tx: Fe deficiency anemia | |
| cyanocobalamin (Vitamin B-12) | hematopoietic/erythrocyte production -Tx: megaloblastic/pernicious anemia (B-12 deficiency) | |
| folic acid (Folvite) | hematopoietic/erythrocyte production -Tx: megaloblastic anemia (folic acid deficiency) | |
| *epoetin alfa | EPO (Epogen, Procrit) | hematopoietic/cytokin-erythrocyte production -Tx: anemia 2ndary to cancer chemotherapy, CRF |
| darbepoetin (Aranesp) | hematopoietic/cytokin-erythrocyte production -Tx: anemia 2ndary to cancer chemotherapy, CRF | |
| filgrastim (Neupogen)/pegfilgrastim (Neulasta) | hematopoietic/cytokin(G-CSF)-leukocyte production -Tx: granulocytopenia, agranulocytosis, or neutropenia after chemotherapy/BMT | |
| sargramostim (Leukine) | hematopoietic/cytokin(G-CSF)-leukocyte production -Tx: granulocytopenia, agranulocytosis, or neutropenia after chemotherapy/BMT | |
| oprelvekin (Neumega) | hematopoietic/cytokin(platelet-CSF)-platelet production -Tx: thrombocytopenia after chemotherapy/BMT | |
| aspirin (ASA) | anticoagulant/anti-platelet -Tx: DVT/PE -MOA: prevent platelet aggregation | |
| *dipyridamole | Persantine | anticoagulant/anti-platelet -Tx: DVT/PE -MOA: prevent platelet aggregation |
| ticlopidine (Ticlid) | anticoagulant/anti-platelet -Tx: DVT/PE -MOA: prevent platelet aggregation | |
| clopidogrel (Plavix) | anticoagulant/anti-platelet -Tx: DVT/PE -MOA: prevent platelet aggregation | |
| eptifibatide (Integrelin) | anticoagulant/anti-platelet(GP IIa/III b blocker) -Tx: DVT/PE -MOA: prevent platelet aggregation by blocking GP IIa /IIIb receptors | |
| tirofiban (Aggrastat) | anticoagulant/anti-platelet(GP IIa/III b blocker) -Tx: DVT/PE -MOA: prevent platelet aggregation by blocking GP IIa /IIIb receptors | |
| abciximab (ReoPro) | anticoagulant/anti-platelet(GP IIa/III b blocker) -Tx: prevent abrupt closure after PTCA(angioplasty) -MOA: prevent platelet aggregation by blocking GP IIa /IIIb receptors | |
| heparin | anticoagulant/heparin -Tx: DVT/PE -MOA: inhibits clotting factors -antidote: protamine | |
| *enoxaparin | Lovenox | anticoagulant/low molecular weight heparin(LMWH) -Tx: DVT/PE -MOA: inhibits clotting factors |
| tinzaparin (Innohep) | anticoagulant/low molecular weight heparin(LMWH) -Tx: DVT/PE -MOA: inhibits clotting factors | |
| dalteparin (Fragmin) | anticoagulant/low molecular weight heparin(LMWH) -Tx: DVT/PE -MOA: inhibits clotting factors | |
| danaparoid (Orgaran) | anticoagulant/low molecular weight heparin(LMWH) -Tx: DVT/PE -MOA: inhibits clotting factors | |
| fondaparinux (Arixtra) | anticoagulant/synthetic heparin analog -Tx: DVT/PE -MOA: inhibits clotting factors | |
| bivalirudin (Angiomax) | anticoagulant/miscellaneous -Tx: DVT/PE -MOA: inhibits clotting factors | |
| *diphenhydramine | Benadryl | antihistamine -Tx: allergic rhinitis, urticaria (hives), pruritus (dermatitis), Ax conjunctiva, Ax (give with EPI if severe),-H1 antagonist -used as OTC sleep aid |