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micro viroids

intro to viroids and prions 3/26

QuestionAnswer
plant pathogens made up of short circular single stranded RNA not surrounded by protein coat Viroids
non cellular hypotroph made up of a nucleic acid core surrounded by a protein coat virus
a complete infective form of a virus as it exists outside of the host is called virion
the sudy of viruses virology
virus that infects bacteria is called bacteriophage
virus that infects E. coli is called coliphage
animal viruses enter their hosts via endocytosis
before the animal virus genome is activated the protein capside is removed by a process called uncoating
a diploid single stranded RNA type virus known as a retrovirus Human Immunodeficiency Virus
How is Human Immunodeficincy Virus a retrovirus it has the ability to reverse transcribe the info of it's viral genome from RNA to DNA
Human Immunodeficiency Virus primary targets T4 lymphocytes
after the virus nucleocapsid enter the host the capsid is removed by a process called uncoating
__ enzyme of HIV caused viral RNA to be reverse transcribed into DNA reverse transcriptase (RNA dependent DNA polymerase)
In HIV the DNA can become integrated into the chromosome of host to form a provirus
integration of viral DNA into host chromosome requires the enzyme ___ integrase
HIV exit the host cell by budding
what causes Acquired Immune Deficiency Syndrome loss of helper T lymphocytes and imbalance within the immune system leaving host subject to infection of many pathogens
double stranded DNA viruses with nyucleocapsideds and envelopes. Has the tendency to go into latent stage following primary infection and reactivate at later times. Herpesviruses (Herpesviridae)
cold sores (fever blisters) and genital that can cross infect Human herpesvirus 1 and 2 (Simplexvirus)-Herpes labialis and genitalis-
caused chickenpox and shingles (zoster) Human herpesvirus 3 (Varicellovirus)-Varicella-zoster virus-
an acute infectious disesase characterized by a maculopapular rash, fever, and respiratory Sx Measeles (Morbillivirus) Rubeola virus
an acute contagious disease characterized by enlargement of salivary glands or glandular tissues Mumps (Rubulavirus)
an acute illness- rash, mild fever, and sore throat. Serious to pregnat women causesin to abnormalities of the ear, eye, heat and nervouse system. German Measles (Rubivirus) Rubella virus
a disease commonly associated with aging people and heritable changes in a cells genetic material cancer
different types of viruses serve as cofactors or cocarcinogens in the development of ___ in humans tumors
segments of DNA that are important players in cancer development oncogenes
___ serve as potential components involved in the conversion of normal cells into cancer cells oncogenes
___ are normal cellular genes that can give rise to cellular or retroviral oncognes proto oncogenes
genes avle to prevent the conversion of normal cells into tumor cells are tumor suppressor genes
viruses have been shown to alter cells through a process called transformation
viruses capable of inducing tumor formation in animals are oncogenic viruses
__ of a virus can be either DNA or RNA (double or single stranded) nucleic acid core or genome
viruses with double stranded RNA the strands are __ and __ complimentary and antiparallel
protein coat surrounding nucleic acid core of a virus capsid
capsid is made up of units called capsomers
capsomers are made up of protein complexes called protomers
many viral capsids are ___ that are spherical in shape polyhedrons
some viruses have an __ outside their protein capsid envelope
capsid and nucleic acide core together are called necleocapsid
___ are attached to the nucleocapsid tail assembly
2 groups of Bacteriophages are cytolytic and temperate bacteriophages
__ causes cell lysis cytolytic bacteriophage
__ does not kill its host right away and may become a prohage temperate bacteriophage
the life cycle starts with a __ outside the cell virion
the binding of a virus to a cells surface is called adsorption
__ involves interaction between the tail fibers and receptors on the host cell surface adsorption
the viral nucleic acid core enters the host cells during penetration
During __ the nucleic acid core enters the host cell penetration
viral nucleic acid is transcribed and translated during latent period or eclipse phase
viral genome is transcribed in 3 parts: immediate early phage genes, delayed arly phage genes, and late phage genes
__ genes encode enzymes that transcribe viral genes and chop up host cells DNA immediate early phage genes
__genes encode enzymes used to replicate the viral genome delayed early phage genes
__ genes encode the proteins needed to build the viral capsid and tail assembly late phage genes
during __ phase the viral components are assembled to form new virons assembly or maturation
proteins that assist in assembling new virions are called chaperonins
__ phase the cell is lysed as viral enzymes soften cell wall and new virions are released release or liberation
temperate phages 2 aka's avirulent or asymptomatic phages
___ is a temperate phage that can become a prophage and also revert to a lytic life cycle bacteriophage lambda
__ gene of Bacteriophage lambda codes for a repressor protein that can block transcription of viral lytic genes cI gene
RecA gene of E. coli codes for __ proteolytic enzyme
__ catalyses the cleavage and inactivation of the cI repressor protein proteolytic enzyme
RecA gene is activated with E. coli cells are in __ conditions stressful
__ occurs when a temperate page genome establishes a stable non lytic relationship with host cell Lysogeny
a bacterium that is carrying a prohage is called a lysogenic cell
the phenotype of bacteria is influenced by the expression of the viral genes lysogenic conversion or bacteriophage conversion
Created by: JohnPink
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