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ABIM - Practice Test

Practice test #3

QuestionAnswer
Sexual interest/arousal disorder lack of sexual interest thoughts or fantasies, dec initiation of sex or dec responsiveness to partner's initiation, dec excitement/pleasure 4 sex, dec response to sex cues, or dec sensations during sex; assoc personal distress is required. Requires 6 mo.
low dopamine transporter uptake in the basal ganglia on single-photon emission CT or PET scans dementia with Lewy bodies
cognitive fluctuations (episodic disorganized speech and functional disability, daytime sleepiness), parkinsonism, visual hallucinations, and severe sensitivity to haloperidol dementia with Lewy bodies
elderly woman w hypothyroidism; 2-week h/o unintentional wt loss, night sweats, and neck swelling. She has more recently also had difficulty swallowing solid foods and positional shortness of breath. thyroid is symmetrically enlarged, firm, and fixed. Primary thyroid lymphoma
How to treat Primary thyroid lymphoma Treatment typically involves chemotherapy and/or radiation therapy. Thyroidectomy is usually not needed.
Presentation of papillary thyroid cancer tumors typically grow very slowly; thyroid is not typically diffusely enlarged, a distinct nodule and potentially concomitant cervical lymphadenopathy would be expected.
Acute onset anterior neck pain. It is typically seen following a viral illness in the preceding months. The changes on CT are typically a patchy infiltrate with minimal lymphadenopathy. Subacute (de Quervain) thyroiditis
Symptoms of a VIPoma watery diarrhea --> dehydration, hypoK, achlorhydria, acidosis, vasodilation (flushing and hypotension), hypercalcemia and hyperglycemia.
What is a VIPoma non-β islet cell of the pancreas, that produce vasoactive intestinal peptide (VIP) causing watery diarrhea --> dehydration, hypoK, achlorhydria, acidosis, vasodilation (flushing and hypotension), hypercalcemia and hyperglycemia.
VIPoma is associated with what MEN I
What is Zollinger Ellison syndrome non–beta islet cell (islet of Langerhans), gastrin-secreting tumor (gastrinoma) in pancreas -> stimulates the parietal cells to release max H+, with consequent gastric/duodenal ulceration and parietal cell hyperplasia
sxs of Zollinger Ellison syndrome abdominal pain and diarrhea, severe ulceration of the stomach and small bowel, especially if they fail to respond to treatment
What syndrome is a gastrinoma associated with MEN I
MEN I PPP Pituitary tumor, pancreatic (gastrinoma, VIPoma) hyperParathyroidism
MEN II PPM Hyperparathyroidism, pheochromocytoma, medullary thyroid cancer
MEN III PMM Pheochromocytoma, Medullary thyroid cancer, Mucosal neuroma
Medullary thyroid carcinoma is associated with what gene? RET Proto oncogene
What will you see on imaging and lab tests for medullary carcinoma of the thyroid? Increased calcitonin and dense calcification in the tumor
What is the treatment for medullary carcinoma? Total thyroidectomy
Why does radio iodine ablation not work for medullary carcinoma of the thyroid? Because radio iodine is not taken up by the cancer cells
How to follow recurrence in medullary carcinoma of the thyroid? Follow calcitonin levels
How you treat for recurrence of medullary thyroid carcinoma? cabozantinib
prior to thyroidectomy in a patient with medullary thyroid carcinoma, what should the patient get? Test plasma fractionated metadata friends to assess for pheochromocytoma. Failure to identify and treat a pheochromocytoma prior to surgery can result in intraoperative hypertensive crisis
Which thyroid cancer has pitted calcifications? Papillary thyroid carcinoma
Papillary thyroid carcinoma is associated with which gene? BRAF
What is the treatment for papillary thyroid carcinoma? Thyroidectomy followed by radio iodine ablation
How do you follow papillary thyroid carcinoma to assess for recurrence? Follow thyroglobulin
How to treat a recurrence of papillary thyroid carcinoma? sorafenib
How does follicular thyroid carcinoma present? A mass with distant metastases
What gene is associated with follicular thyroid carcinoma? RAS
How to treat follicular thyroid carcinoma Thyroidectomy followed by radio iodine ablation
How to follow recurrence of follicular thyroid carcinoma? Follow thyroglobulin level
How to treat a recurrence of follicular thyroid carcinoma? sorafenib
Who usually got anapestic carcinoma of the thyroid? Presents as a mass in the elderly, worst prognosis
Created by: christinapham