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Renal - ABIM
Nephritis Nephropathy
| Question | Answer |
|---|---|
| What disease has low C3 and normal C4? | Post infectious glomerulonephritis |
| What disease has very low C3 and slightly low C4? | SLE nephritis |
| What disease has slightly low C3 and very low C4? | Membranoproliferative glomerulonephritis MPGN |
| Cryoglobulinemia is associated with what two diseases? | Hepatitis C and membranoproliferative glomerulonephritis |
| Foot drop, livedo reticularis, infections in the ear, leukocytoclastic vasculitis. What disease? | Cryoglobulinemia |
| What disease has tram tracking, and what makes up the tram tracks? | MPGN, membranoproliferative glomerulonephritis. Tram tracking is the separation of the basement membrane with mesangial growth between the two layers of the basement membrane. |
| Which disease has sub endothelial deposits? Which disease has sub epithelial deposits? | Membranoproliferative glomerulonephritis has sub endothelial deposits. Post infectious glomerulonephritis has sub epithelial deposits. |
| How do you treat MPGN, membranoproliferative glomerulonephritis? | First try steroids. If that doesn't work, then cyclophosphamide – consider adding aspirin |
| Which diseases is membranoproliferative glomerulonephritis associated with? | C B C SLE SBE. Hepatitis C more than hepatitis B; cryoglobulinemia; lupus; subacute bacterial endocarditis |
| How would you follow treatment success in lupus nephritis? | Anti DS DNA |
| What would you find in the urine of lupus nephritis? | Protein of greater than 524 hours, greater than 10 RBCs I'm urinalysis, RBC/WBC/granular casts |
| What would you find on immunofluorescence in post infectious glomerulonephritis? | Granular, lumpy bumpy pattern |
| Name the six pulmonary renal syndromes | Lupus nephritis, anti- glomerular basement membrane, microscopic polyarteritis angiitis, polyarteritis nodosa, eosinophilic granulomatosis with polyangiitis (Churg Strauss), granulomatosis with polyangiitis (Wegner's) |
| What disease when you have a patient with a URI that then has hematuria and rbc casts | IgA nephropathy |
| If a kidney biopsy shows IgA deposits with proliferation of been the sand GM, what do you treat the patient with? | ACEi and maybe steroids if needed (patient has IgA nephropathy) |
| What is the formula for the serum ascities albumin gradient? | (serum albumin) – (ascites albumin) = SAAG |
| What is in the differential for SAAG >1.1 with protein <2.5 | more albumin in the serum – Cirrhosis |
| What is in the differential for SAAG <1.1 with protein <2.5 | More albumin in the ascites - nephrotic syndrome or myxedema |
| What is in the differential for S AAG >1.1 with protein >2.5 | More albumin in the serum – cardiac or Budd-Chiari (portal vein thrombosis) |
| What is in the differential for S AAG <1.1 with protein >2.5 | More albumin in the ascites - infections, malignancy, pancreatic |
Created by:
christinapham
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