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Renal - ABIM

Nephritis Nephropathy

QuestionAnswer
What disease has low C3 and normal C4? Post infectious glomerulonephritis
What disease has very low C3 and slightly low C4? SLE nephritis
What disease has slightly low C3 and very low C4? Membranoproliferative glomerulonephritis MPGN
Cryoglobulinemia is associated with what two diseases? Hepatitis C and membranoproliferative glomerulonephritis
Foot drop, livedo reticularis, infections in the ear, leukocytoclastic vasculitis. What disease? Cryoglobulinemia
What disease has tram tracking, and what makes up the tram tracks? MPGN, membranoproliferative glomerulonephritis. Tram tracking is the separation of the basement membrane with mesangial growth between the two layers of the basement membrane.
Which disease has sub endothelial deposits? Which disease has sub epithelial deposits? Membranoproliferative glomerulonephritis has sub endothelial deposits. Post infectious glomerulonephritis has sub epithelial deposits.
How do you treat MPGN, membranoproliferative glomerulonephritis? First try steroids. If that doesn't work, then cyclophosphamide – consider adding aspirin
Which diseases is membranoproliferative glomerulonephritis associated with? C B C SLE SBE. Hepatitis C more than hepatitis B; cryoglobulinemia; lupus; subacute bacterial endocarditis
How would you follow treatment success in lupus nephritis? Anti DS DNA
What would you find in the urine of lupus nephritis? Protein of greater than 524 hours, greater than 10 RBCs I'm urinalysis, RBC/WBC/granular casts
What would you find on immunofluorescence in post infectious glomerulonephritis? Granular, lumpy bumpy pattern
Name the six pulmonary renal syndromes Lupus nephritis, anti- glomerular basement membrane, microscopic polyarteritis angiitis, polyarteritis nodosa, eosinophilic granulomatosis with polyangiitis (Churg Strauss), granulomatosis with polyangiitis (Wegner's)
What disease when you have a patient with a URI that then has hematuria and rbc casts IgA nephropathy
If a kidney biopsy shows IgA deposits with proliferation of been the sand GM, what do you treat the patient with? ACEi and maybe steroids if needed (patient has IgA nephropathy)
What is the formula for the serum ascities albumin gradient? (serum albumin) – (ascites albumin) = SAAG
What is in the differential for SAAG >1.1 with protein <2.5 more albumin in the serum – Cirrhosis
What is in the differential for SAAG <1.1 with protein <2.5 More albumin in the ascites - nephrotic syndrome or myxedema
What is in the differential for S AAG >1.1 with protein >2.5 More albumin in the serum – cardiac or Budd-Chiari (portal vein thrombosis)
What is in the differential for S AAG <1.1 with protein >2.5 More albumin in the ascites - infections, malignancy, pancreatic
Created by: christinapham