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Patho Kaplan key wor
clinical presentation
| Question | Answer |
|---|---|
| .Cell swelling | Reversible damage/Inhibition of Na/K/ATPase |
| BAX and BAK | Pro-apoptotic |
| Caspase activation causes | apoptosis |
| .Free copper or iron | Free radical production |
| Superoxide dismutase | Neutralizes superoxides |
| Decrease oxygen content Increase EPO | |
| NADPH oxydase reaction produces what | Superoxide by leukocytes |
| Glutathione peroxidase | Neutralization of OH. H202. NAPQI |
| BCL-2 | Antiapoptotic |
| Ca/ATPase inhibition . | Irriversible damage |
| Cytochrom C leakage ' | apoptosis |
| Most damaging free radical | Hydroxyl free radical |
| Leakage of intracellular enzymes . | Membrane damage |
| Growth of a tissue by replicating the cells | Hyperplasia |
| Low Hb ,SaO2 and PaO2 | |
| Decrease arterial flow or venous outflow . | ischemia |
| Catalase neutralizes what | H202 to H20 and 02 |
| Ionizing radiations ' | Hydroxyl free radical |
| Cell death without inflammation ' | Apoptosis |
| Coagulative necrosis with cheese like material in the center | Caseous necrosis |
| Disordered cell growth | Dysplasia |
| Change of one epithelium to a different type as adaptation ' | Metaplasia |
| Tissues that can only hypertrophy (3) | Heart. skeletal muscle, neurons |
| Leakage of intracellular enzymes . | Membrane damage |
| Growth of a tissue by replicating the cells | Hyperplasia |