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Patho Kaplan key wor

clinical presentation

.Cell swelling Reversible damage/Inhibition of Na/K/ATPase
BAX and BAK Pro-apoptotic
Caspase activation causes apoptosis
.Free copper or iron Free radical production
Superoxide dismutase Neutralizes superoxides
Decrease oxygen content Increase EPO
NADPH oxydase reaction produces what Superoxide by leukocytes
Glutathione peroxidase Neutralization of OH. H202. NAPQI
BCL-2 Antiapoptotic
Ca/ATPase inhibition . Irriversible damage
Cytochrom C leakage ' apoptosis
Most damaging free radical Hydroxyl free radical
Leakage of intracellular enzymes . Membrane damage
Growth of a tissue by replicating the cells Hyperplasia
Low Hb ,SaO2 and PaO2
Decrease arterial flow or venous outflow . ischemia
Catalase neutralizes what H202 to H20 and 02
Ionizing radiations ' Hydroxyl free radical
Cell death without inflammation ' Apoptosis
Coagulative necrosis with cheese like material in the center Caseous necrosis
Disordered cell growth Dysplasia
Change of one epithelium to a different type as adaptation ' Metaplasia
Tissues that can only hypertrophy (3) Heart. skeletal muscle, neurons
Leakage of intracellular enzymes . Membrane damage
Growth of a tissue by replicating the cells Hyperplasia
Created by: Hsp128



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