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succinylcholine

succs

QuestionAnswer
GENERIC NAME Succinylcholine
BRAND NAME Anectine
CLASS Depolarizing paralyzing agent
MECHANISM OF ACTION Binds to the receptors for acetylcholine
INDICATIONS To facilitate intubation, to terminate laryngospasm, to promote muscle relaxation, to facilitate electroconvulsive shock therapy.
CONTRAINDICATIONS Acute narrow-angle glaucoma. Penetrating eye injuries, inability to control airway or support ventilations with oxygen and positive pressure.
ADVERSE REACTIONS Apnea, Malignant Hyperthermia, arrhythmias, Bradycardia, hypertension, hypotension, cardiac arrest, Hyperkalemia, increased intraocular pressure, fasciculations, exacerbation of Hyperkalemia in trauma patients.
NOTES ON ADMINISTRATION Pregnancy Category C. Ems use primarily to facilitate intubation. If conscious explain effects of drug. Consider premedication with atropine. Premedication with lidocaine may blunt any increase in intracranial pressure during intubation.
INCOMPATABILITIES/DRUG INTERACTIONS Effects potentiated by oxytocin, beta blockers, and organophosphates. Diazepam may reduce the duration of action.
DOSE/ROUTE, ADULT 1-2mg/kg rapid IV. Repeat once if needed.
DOSE/ROUTE, PEDIATRIC 1-1.5 mg/kg rapid IV/IO. Repeat once if needed.
ONSET OF ACTION 1 minute
PEAK EFFECTS 1-3 minutes
DURATION OF ACTION 5 minutes
AZ DRUG BOX SUPPLY RANGE 400mg.
Created by: klindley