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Glucagon

glucagon

QuestionAnswer
GENERIC NAME None
BRAND NAME Glucagon
CLASS Hyperglycemic agent, pancreatic hormone, insulin antagonist
MECHANISM OF ACTION Increases blood glucose level by stimulating glycogenolysis. Unknown mechanism of stabilizing cardiac rhythm in beta blocker overdose. Minimal positive inotropic and chronotropic effect. Decreases GI motility and secretions.
INDICATIONS ALOC why hypoglycemia is suspected. May be used as an inotropic agent in beta blocker overdose.
CONTRAINDICATIONS Hyperglycemia, hypersensitivity
ADVERSE REACTIONS N/V tachycardia, hypertension
NOTES ON ADMINISTRATION Pregnancy category C. should always be used in conjunction with 50% dextrose whenever possible.
INCOMPATABILITIES/DRUG INTERACTIONS Incompatible in solution with most other substances. No significant drug interactions with other emergency medications.
DOSE/ROUTE, Adult, Hypoglycemia 0.5-1mg IM. May repeat in 7-10 minutes.
Adult, Calcium channel blocker or beta blocker overdose 3mg initially,followed by an infusion at 3mg/hr as necessary.
Pediatric, hypoglycemia 0.5-1mg IM.
Pediatric, calcium channel blocker and beta blocker overdose Not recommended.
ONSET OF ACTION 1 minute
PEAK EFFECTS 30 minutes
DURATION OF ACTION Variable
AZ DRUG BOX SUPPLY RANGE 2mg.
Created by: klindley