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Glucagon
glucagon
Question | Answer |
---|---|
GENERIC NAME | None |
BRAND NAME | Glucagon |
CLASS | Hyperglycemic agent, pancreatic hormone, insulin antagonist |
MECHANISM OF ACTION | Increases blood glucose level by stimulating glycogenolysis. Unknown mechanism of stabilizing cardiac rhythm in beta blocker overdose. Minimal positive inotropic and chronotropic effect. Decreases GI motility and secretions. |
INDICATIONS | ALOC why hypoglycemia is suspected. May be used as an inotropic agent in beta blocker overdose. |
CONTRAINDICATIONS | Hyperglycemia, hypersensitivity |
ADVERSE REACTIONS | N/V tachycardia, hypertension |
NOTES ON ADMINISTRATION | Pregnancy category C. should always be used in conjunction with 50% dextrose whenever possible. |
INCOMPATABILITIES/DRUG INTERACTIONS | Incompatible in solution with most other substances. No significant drug interactions with other emergency medications. |
DOSE/ROUTE, Adult, Hypoglycemia | 0.5-1mg IM. May repeat in 7-10 minutes. |
Adult, Calcium channel blocker or beta blocker overdose | 3mg initially,followed by an infusion at 3mg/hr as necessary. |
Pediatric, hypoglycemia | 0.5-1mg IM. |
Pediatric, calcium channel blocker and beta blocker overdose | Not recommended. |
ONSET OF ACTION | 1 minute |
PEAK EFFECTS | 30 minutes |
DURATION OF ACTION | Variable |
AZ DRUG BOX SUPPLY RANGE | 2mg. |