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MSII Unit 2 Pharm

Care of Pt. w/ a blood or lymphatic disorder

QuestionAnswer
Warfarin and anisindione interfere with the manufacturing of.(Pg.467) Vitamin K-dependent clotting factors by the liver.
heparin cannot be taken orally because..(pg.467) it is inactivated by gastric acid in the stomach; therefore it must be given by injection.
the action of heparin inhibits the formation of...(pg.467) fibrin clots, inhibits the conversion of fibrinogen to fibrin, and inactivates several of the facors necessary for clotting of the blood.
The low-molecular-weight heparins (LMWHs)act to inhibit...(pg.467) clotting reation by binding to antithrombin III, which inhibits the synthesis of factor X and the formation of thrombin.
The principle adverse reaction associated with anticoagulants is..(pg.467) Bleeding
Oral agents for anticoagulants are Pregnancy Category..(pg.467) X
Antiplatelet drug therapy is designed primarily to treat pt.s at risk for..(pg.470) acute coronary syndrome, MI, stroke, and intermittent claudication.
Antiplatelet drugs should be discontinued...(pg.471) 1 week before a surgical procedure... and stopped immediately if thrombocytopenic purpura (TTP) is diagnosed.
this class of drugs dissolve blood clots that have already formed within the cell walls os a blood vessel...(pg471) Thombolytic drugs. HINT: these drugs us ASE at the end of each drug name.
The most COMMONLY used test to monitor heparin is the..(pg.472) activated partial thromboplastin time (APTT)
before administering the first dose of an anticoagulant or thrombolytic, the nurse..(pg.472) questions the pt about all drugs taken during the previous 2-3 weeks.
before the administration of the thrombolytic agents..(pg.472) Blood for a complete blood count(CBC) is drawn.
before administering each dose of warfarin, the nurse checks..(pg.473) the prothrombin flow sheet or the laboratory report to review the current PT/INR results.
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