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Adenosine

drug sheet

QuestionAnswer
Adenosine other names Adenocard
Class: Antiarrhythmic
Pharmacology and Actions A. Endogenous nucleoside – present in all cell bodies
Pharmacology and Actions B. Slows conduction time through the A-V node
Pharmacology and Actions C. Can interrupt reentry pathways through the A-V node
Pharmacology and Actions D. Removed rapidly from circulation by erythrocytes and vascular endothelial cells. Half life is less than 10 seconds
Indications A. PSVT, SVT
Indications B. PSVT associated with WPW
Contraindications A. Does not convert Atrial Flutter, Atrial Fibrillation, or Ventricular Tachycardia
Contraindications B. Second or third degree A-V block
Contraindications C. Sick sinus syndrome
Precautions and Side Effects A. Antagonized by caffeine and theophylline due to prevention of adenosine binding at receptor sites. May need larger dose.
Precautions and Side Effects B. Potentiated by dipyridamole (persantine). May need smaller dose.
Precautions and Side Effects C. May produce a short lasting first, second, or third degree heart block
Precautions and Side Effects D. In extreme cases it may cause prolonged asystole.
Precautions and Side Effects E. May produce arrhythmias at the time of conversion which should only last a short while including PVC’s, PAC’s, sinus brady, sinus tach, skipped beats and varying degrees of A-V blocks
Precautions and Side Effects F. Tegretol may result in development of high-degree blocks. May need smaller dose.
Precautions and Side Effects G. May cause dizziness, flushing, HA, numbness in arms, dyspnea, chest pain, palpitations, nausea, chest pressure, bronchospasm, feeling of impending doom and heaviness in arms and neck
Dosages and supplied 1st dose 6mg push, 2nd & 3rd dose 12mg. max 30mg..... supplied 6mg/2ml or 12mg/4ml
Created by: shonnc