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Cardiac Drugs
Anti-Hypertensives
| Question | Answer |
|---|---|
| blocks enzyme that converts agiotension I to angiotension II. Keeps vessels open and compliant | ACE-Inhibitor |
| suffix "pril" | ACE-Inhibitor |
| drug that causes potassium retention | ACE-Inhibitor |
| Hypertension can occur when fist taking these drugs. START LOW, GO SLOW | ACE |
| decrease aldosterone production | ACE |
| can cause or aggravate protenuria and renal damage in non-diabetics and can have the opposite affects on diabetics | ACE |
| First-Line treatment drug for diabetics | ACE |
| Persistent cough develops in 10-20% of ppl | ACE |
| Hyperkalemia can happen with this drug | ACE |
| Less effective with AA as monotherapy | ACE |
| Patients with this drug often experience increase in BUN and serum creatinine levels | ACE |
| Dosage needs to be reduced in ppl with renal failure | ACE |
| Adjust or discontinue dosage with ppl who have hepatic failure | ACE |
| Work on Angiotension II | ARBs |
| "sartan" is the suffix here | ARBs |
| less likely to cause hyperkalemia and cough causing effects are less | ARBs |
| Losartan has max effects on BP in 3-6 weeks | ARBs |
| metabolized in the liver and do not need dose reduction with renal impairment | ARBs |
| Inhibit activity of SNS | Antiadrenergic |
| adverse effect is OSHT called the first dose phenomenon | Antiadrenergic |
| take first dose at night to prevent first-dose-phenomenon | Antiadrenergic |
| long-term use may warrant diuretic therapy be added due to sodium and fluid retention | Antiadrenergic |
| decreases sympathetic activity causing decreased CO, HR, BP, and PVR | Clonidine (Catapres) (alpha-2) |
| dilates blood vessels and decreases PVR | Prazosin (Minipres) (alpha-1) |
| given to AA who do not respond to ACE and ARBs, give these bc they have low renin-hypertension | Antiadrenergic |
| Effects the SNS. May cause you to be drowsy, dizzy, palpitations, and syncope | Antiadrenergic |
| Disadvantage is the delayed onset of effect usually 2-3 days for TD. PO usually takes affect within 1-3 hours | Antiadrenergic |
| Decrease heart rate, force of MI contraction, CO, and rennin release from the kidneys | Beta-Adrenergic Blockers |
| Abrupt withdrawl has resulted in exacerbation of angina, the incidence of ventricular dysrhythmias and the occurrence of MIs | Beta-Adrenergic Blockers |
| "olol" | Beta-Adrenergic Blockers |
| More effective than nitrates or calcium channel blockers in decreasing the likelihood of silent ischemia and improving the mortality rate after tansmural MI | Beta-Adrenergic |
| Don't give to someone who has pulmonary disease bc it is nonselective | Beta-Adrenergic Blockers |
| selective for beta-1 | Atenolol (Tenormin) and Lopressor (metoprolol) |
| first choice for patients younger than 50 with high rennin-hypertension, tachycardia, angina pectoris, MI, or left ventricular hypertrophy | Beta-Adrenergic |
| used in children of all ages for hypertension and HA | Beta-Adrenergic |
| take this med on empty stomach | Catopril |
| in hypertension, these drugs mainly dilate peripheral arteries and decrease PVR by relaxing vascular smooth muscle | Calcium Channel Blockers |
| well absorbed from the GI tract following oral administration and are highly protein bound | Calcium Channel Blockers |
| Not a first choice drug for angina | Calcium Channel Blockers |
| Commonly prescribed in combination with beta blockers | Calcium Channel Blockers |
| Cardiac Selected drugs | Calcium Channel Blockers |
| Drug of choice for AA with stage II hypertension | Calcium Channel Blockers |
Created by:
jenetheridge77
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