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Ipratropium Bromide

CLASS anticholinergic, bronchodilator
MECHANISM OF ACTION Anticholinergic (parasympatholytic) agent appears to inhibit vagally-mediated reflexes by antagonizing the action of acetylcholine, the transmitter released from the vagal nerve.
INDICATIONS Treatment of bronchospasm associated with chronic obstructive pulmonary disease (emphysema and chronic bronchitis). To be used either alone or in combination with other bronchodilators especially beta adrenergics (i.e., albuterol).
CONTRAINDICATIONS Ipratropium bromide is contraindicated in known or suspected cases of hypersensitivity to ipratropium bromide or to atropine and its derivatives. Precaution
ADVERSE REACTIONS Coughing, Increased Sputum, Dizziness, Insomnia, Tremor, Nervousness,Nausea
INCOMPATABILITIES/DRUG INTERACTIONS None. Ipratropium bromide has been shown to be safe and effective bronchodilator when used in conjunction with beta adrenergic bronchodilators (albuterol)
DOSE/ROUTE Give 500 mcg in 2.5 ml normal saline (1 unit dose vial) via SVN with a mouth piece or in-line with a ventilatory device. Repeat according to medical control preference. May mix one unit dose vial of ipratropium with one unit dose vial of albuterol.
ONSET OF ACTION 5-15 minutes
PEAK EFFECTS 60-120 minutes
DURATION OF ACTION 240-480 minutes
Created by: klindley



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