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Genes for Embryogen
FA Repro
| Question | Answer |
|---|---|
| produced at base of the limbs in zone of polarizing activity | Sonic Hedgehog gene |
| patterning along anterior posterior axis | Sonic Hedgehog gene |
| CNS development | Sonic Hedgehog gene |
| Mutation can cause holoprosencephaly | Sonic Hedgehog gene |
| Produced at apical ectodermal ridge | WNT-7 and FGF gene |
| necessary for proper organization along dorsal-ventral axis | Wnt7 |
| stimulates mitosis of underlying mesoderm providing limb lengthening | FGF |
| segmental organization of embryo in craniocaudal direction | Hox |
| codefor transcription factors | Hox |
| mutation: appendages at wrong location | Hox |