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Immuno Complement

Complement cleavage products & their activities

Opsonization of antigen C3b & C4b Increased phagocytosis by macrophages & neutrophils
Chemotaxis C3a & C5a Attraction of neutrophils & monocytes to inflammatory site
Degranulation C3a & C5a (anaphylotoxins) Release of inflammatory mediators from mast cells & basophils
Clearance of immune complexes C3b Reduced buildup of potentially harmful Ag-Ab complexes
B cell activation C3d Promotiono of humoral immune response
Created by: catatonic14