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Med Biochem

Vitamins

Vitamin Other names Deficiency Functions Solubility
Vitamin C Ascorbic Acid Scurvy ( sore, spongy gums) Antioxidant & Cofactors Water soluble
Vitamin B6 Pyridoxine Rare ( mild:personality disorder,dermatitis,glossitis) (severe:peripheral neuropathy, seizures, sideroblastic anemia) Cofactors for enzymes in AA metabolism Water soluble
Vitamin B1 Thiamine Beriberi ( dry & wet) ( tachycardia, vomiting, neuropathy) Cofactor Water soluble
Niacin ( B3) Nicotinic Acid Pellagra (3D's: Diarrhea, Dermatitis, Dementia) Electron Transfer Water soluble
Vitamin B2 Riboflavin Rare Electron Transfer Water soluble
Biotin N/A Rare Carboxylation Reactions Water soluble
Pantothenic Acid N/A Rare Acylcarrier Water soluble
Vitamin D Cholecalciferol (1,25-OH D3--> Active form via kidney) Rickets (in children) Osteomalacia (in adults) Calcium Uptake Fat soluble
Vitamin K Menadione Bleeding In newborns Rarely In adults ( can be due to broad spectrum antibiotics) Carboxylation in clotting and other proteins Fat soluble
Vitamin E α-Tocopherol Found deficient in : Cystic fibrosis & celiac Spure Antioxidant Fat Soluble
Folic Acid N/A NTD's synthesis of purines and methionine Water soluble
Vitamin B12 Cobalamin (Pernicious anemia) Spinal Degeneration Cofactors for enzymes Water soluble
Vitamin A Retinol Retinal Retinoic acid B-carotene(not active) Impotence, Night blindness, Retardation of growth, Eye abnormalities Reproduction , Vision , Growth , Gene Expression Fat soluble
Created by: osabdelr