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Endocrinology
Hormones
| Question | Answer |
|---|---|
| Endocrine is used for | communiticating with the rest of the body, its one of two systems. |
| Hormones come in two major forms: | petides/proteins and amins (growth hormone, insultin, oxytocin, epinephrine) and lipid based hormones (steroids, prostaglandins and amines) |
| Endocrine signaling | generic endocrine pathway-diffuse into the blood and trigger a response in the body somewhere |
| Paracrine signaling | diffuse locally parachuting into where needed and tiggering a response in neighboring. |
| Autocrine signaling | secreted to trigger the cells to start secreting themselves. |
| Synaptic signaling | Neurotransmitors diffuse across syanpas and trigger a response in the target tissue, work on neurons, muscles and shit |
| Neuroendocrine signaling | is a neurohormone |
| Amplification | signal-transduction pathways allow for small amounts of a hormone to have a large effect |
| REceptors are | large protein found in the membrane surface or cytoplamic surface or the nuclear one. |
| Peptide hormones usually act with a | membrane receptor because these are water soluble hormones that can't diffuse across the lipid layer |
| Steroid hormones interact with | nuclear receptors, because they are fat soluble hormones and usually have to do with transcription factors so need to got the nuclear region anyways. |
| Hypothalmus | third ventricle of the brain secretes hormones that influence the synthesse and release of pituitary hormones (GnRH, TRH, and dopamine) Goes into the blood vessel system between hypothalmus and pituitary. |
| Pituitary has two parts the | adenohypophysis (anterior) and neurohypophysis (posterior) |
| Thyroid | two lobes in the neck, controls hormones Thyroxine and triiodothyronine which need iodine. Controls metablosim and developement of the nervous system. |
| Endocrine Pancreas | Two hormones produced in Islets of Langerhans (glucogan and insulin) |
| Andrenal | associated with kidneys, produces steroid hormones and plays a major role in stress response. |
| Andrenal has two parts | Andrenal cortex-outer layer, the true endocrine cells, and the andrenal medula which is the central portion |
| Gonadotrpin stimulates ... and is stimulted by | Gonadotropin stimulates the gonads and is stimulated by the FSH and LH |
| Follicle stimulating hormone | stimulates gametogenesis or the growth of follicles in both male and female |
| Luteinizing hormones | stimulates all th steroids needed for girls and boys lubing it up |
| Prolactin | stimulates lacting, who'd have thoght |
| Oxytocin | stimulates contractions, to much can have the reverse effect |
| Prostaglandins | found virtually in all tissues and organs, prostaglandins are in NSAID because block COX aspect of the swelling and inflammation. |