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Integumentary System

Tumor Grading

Grade I close resemblance to tissue of origin and, thus, retaining some specialized functions
Grade I tumor cells well differentiated
Grade II tumor cells moderately or poorly differentiated
Grade II less resemblance to tissue of origin
Grade II more variation in size and shape of tumor cells
Grade II increased mitoses
Grade III tumor cells poorly differentiated
Grade III increased abnormality in appearance with only remote resemblance to the tissue of origin
Grade III marked variation in shape and size of tumor cells
Grade III greatly increased mitosis
Grade IV abnormal appearance to the extent that recognition of the tumor's tissue origin is difficult
Grade IV tumor cells very poorly differentiated
Grade IV Extreme variation in size and shape of tumor cells