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Microb/Immuno 2

First Aid Q&A: Microbiology & Immunology 2

What is the treatment for food poisening resulting from reheated rice? B. cereus enterotoxin; treatment with supportive therapy as this is a preformed enterotoxin so antibiotics are ineffective
What autoantibodies are associated with microscopic polyangitis, a form of polyarteritis nodosa? Perinuclear antineutrophil cytoplasmic autoantibodies (P-ANCA); Not necessarily related to classic polyarteritis nodosa, just microscopic polyangitis
What autoantibodies are associated with Wegeners granulomatosis? Circulating antineutrophil cytoplasmic autoantibodies (C-ANCA)
This gram positive cocci is a common cause of nosocomial urinary tract infections and subacute endocarditis. Enterococcus, treated with ampicillin
What type of graft is from an identical twin sibling? Syngeneic graft
What type of graft is from the same species? Allogenic or homograft
What type of graft is from the patients own tissue? Autologous graft
What type of graft is taken from a different species? heterograft (also called xenogenic graft)
What is the most common cause of bacterial meningitis ages 6 months to 6 years? Streptococcus pneumoniae
What is the treatment for chlamydia urethritis? Azithromycin or doxycycline
Which is more likely to present with systemic symptoms and large joint involvement, patients with juvenile rheumatoid arthritis or adult onset rheumatoid arthritis? JRA
Syndrome is characterized by IgG autoantibodies forming against glomerular basement membrane resulting in a linear pattern on immunofluorescence. Goodpastures syndrome
What type of hypersensitivity is associated with serum sickness? Type III; immune complex formation
What type of hypersensitivity is associated with delayed (cell mediated) reactions? Type IV; T lymphocytes release lymphokines in response to antigen as opposed to the other 3 types which are all antibody mediated
What type of hypersensitivity is associated with IgE crosslinking leading to release of vasoactive amines? Type I; anaphylactic reaction
What type of hypersensitivity is associated with antibody activation of cytotoxic T cells? Type II; antibody mediated cytotoxicity
Patient presents with recurrent pyogenic infections, pruritic papulovesicular dermititis, and thrombocytopenia. Diagnosis? Wiskott-Aldrich syndrome
Patient presents with hepatomegaly, splenomegaly, malaise, anemia, and weight loss after a trip to africa. Amastigotes are seen microscopically within macrophages. Diagnosis and treatment? L. Donovani infection; sodium stibogluconate
What is the treatment for toxoplasmosis? Sulfadiazine and pyrimethamine
What is the surface antigen found on pluripotent stem cells? CD34
What is the surface antigen found on helper T lymphocytes? CD4
What is the surface antigen found on cytotoxic T cells CD8
What is the surface antigen found on APC's and what receptor does it bind on T lymphocytes? B7 binds CD28 on helper T lymphocytes
What virus commonly causes retrosternal pain radiating to back and arms that worsens on inspiration, also high pitched grating sound on lower left sternal border? Clinical picture is of pericarditis; Common viral etiologic agent is coxsackie virus
Patient with a reaction to poison ivy has what type of hypersensitivity reaction? Type IV; this means that the patient does not have a reaction on first exposure, but on second exposure symptoms will manifest (delayed)
Patient presents with diplopia and dysphagia, followed by general muscle weakness and respiratory muscle paralysis. Significant history of consumption of homemade jam. Etiologic agent? Cloistridium botulinim
Patient presents with tender, swollen, and red left knee. Aspirate of synovial fluid is yellow and turbid (cloudy) with neutrophils predominant. Gram positive cocci also present. Etiologic agent? Septic arthritis; commonly caused by S. aureus
An 8 yro boy presents with fever, sore throat, tonsillar exudates, tender anterior cervical lymph nodes. Etiologic agent? Classic strep throat; Streptococcus pyogenes
What are the three vasculitides associated with antineutrophil cytoplasmic antibodies (ANCA)? Microscopic polyangiitis, Wegener's granulomatosis and Churg-Strauss syndrome
Created by: rahjohnson



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