Save
Upgrade to remove ads
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Diabetes Meds

Diabetes

QuestionAnswer
Biguanide Metformin - Target is the liver to reduce overproduction of glucose. Max effective dose 2000mg/day
Sulfonyureas Glimeperide/amaryl, Glipizide/glucotrol (has xr), Glyburide/diabeta;micronase Target beta cells in pancreas to increase secretion
Sulfonylureas Increase insulin secretion, take 30 min before meal
Metformin Side Effects GI (nausea/diarrhea), R/F lactic acidosis; monitor Creatinine as it is cleared by kidneys (avoid in women if >1.4, men if >1.5)
Metformin Advantages Cost, no weight gain, reduces LDL & Triglycerides, low r/f hypos
Glimeperide Sulfonylurea, increase insulin secretion
Glipizide Sulfonylurea, increase insulin secretion, comes in XR too
Glyburide Sulfonylurea, increase insulin secretion
Sulfonylurea side effects R/F hypoglycemia, do not skip meals, Weight gain (1-2kg)
Thiazolidiones (TZD's) Pioglitizone/actos; Rosiglitazone/avandia. Targets muscles & liver, insulin sensitizer. Takes 8-12 weeks for full effect, take w/o regard to meals
Actos (pioglitazone) TZD, insulin sensitizer, taken daily, low r/f hypo
Avandia (rosiglitazone) TZD, insulin sensitizer, taken daily or BID, low r/f hypo
TZD side effects Fluid retention/edema, weight gain common (water retention + increase fat mass), fractures r/t slowing of protein building in bone, low r/f bladder ca
DPP IV Inhibitors Sitagliptin/januvia, Saxagliptin/onglyza, Linagliptin/tradjenta, Alogliptin/nesina. Targets gut & pancreas. Inhibits glucagon release, stimulates insulin release, delays gastric emptying
Sitagliptin/januvia DPP IV Inhibitor. Targets gut & pancreas. Inhibits glucagon release, stimulates insulin release, delays gastric emptying
Saxagliptin/onglyza DPP IV Inhibitor. Targets gut & pancreas. Inhibits glucagon release, stimulates insulin release, delays gastric emptying
Linagliptin/tradjenta DPP IV Inhibitor. Targets gut & pancreas. Inhibits glucagon release, stimulates insulin release, delays gastric emptying
Alogliptin/nesina DPP IV Inhibitor. Targets gut & pancreas. Inhibits glucagon release, stimulates insulin release, delays gastric emptying
DPP IV Inhibitor side effects Consider renal adjustments based upon Creatinine clearance
DPP IV Inhibitor advantages No weight gain, low r/f hypoglycemia, usually no n/v, oral
GLP-1 Exenatide/byetta & bydureon ER, Liraglutide/victoza, Albiglutide/tanzeum, Dulaglutide/trulicity. Targets pancreas & gut to stimulate insulin secretion, suppress glucagon secretion, slow gastric emptying/increased satiety. Injectable
Exenatide/byetta&bydureon(er) INJECTABLE. Targets pancreas & gut to stimulate insulin secretion, suppress glucagon secretion, slow gastric emptying/increased satiety.
Liraglutide/victoza INJECTABLE. Targets pancreas & gut to stimulate insulin secretion, suppress glucagon secretion, slow gastric emptying/increased satiety.
Albiglutide/tanzeum INJECTABLE. Targets pancreas & gut to stimulate insulin secretion, suppress glucagon secretion, slow gastric emptying/increased satiety.
Dulaglutide/trulicity INJECTABLE. Targets pancreas & gut to stimulate insulin secretion, suppress glucagon secretion, slow gastric emptying/increased satiety.
GLP-1 Advantages Daily and weekly injection options, weight friendly
GLP-1 side effects N/V/D, hypoglycemia, slows absorption of other drugs
SGLT2 Inhibitors Canagliflozin/invokana, Dapagliflozin/farxiga, Empagliflozin/jardiance. Targets proximal tubule inhibiting glucose reabsorption & increasing glycosuria.
Canagliflozin/invokana Targets proximal tubule inhibiting glucose reabsorption & increasing glycosuria. 100-300mg daily
Dapagliflozin/farxiga Targets proximal tubule inhibiting glucose reabsorption & increasing glycosuria. 5-10mg daily
Empagliflozin/jardiance Targets proximal tubule inhibiting glucose reabsorption & increasing glycosuria. 10-25mg daily
SGLT2 Inhibitor side effects Genital mycotic infections, primarily in females & uncircumcised males. Osmotic diuresis
Amylin Analog Pramlintide/symlin. Targets pancreas, liver, gut to suppress glucagon secretion, decrease hepatic glucose output, slow gastric emptying. INJECTABLE taken prior to major meals
Pramlintide/symlin Amylin Analog, given in conjunction with insulin. Decrease preprandial insulin by 50% at initiation. If Type 1DM 15mcg-60mcg, 4step titration, if Type 2 DM 60mcg-120mcg, 2step titration. Increase dose every 3-7 days depending on GI tolerance.
AGI's (alpha-glucosidase inhibitors) Acarbose/precose, Miglitol/glyset. Target gut enzymes, delays carbohydrate absorption due to inhibition of enzymes.
Acarbose/precose AGI. Target gut enzymes, delays carbohydrate absorption due to inhibition of enzymes.
Miglitol/glyset AGI. Target gut enzymes, delays carbohydrate absorption due to inhibition of enzymes.
AGI side effects Gas; bloating r/t fermentation of carbs
Non-sulfonylurea Repaglinide/prandin, Nateglinide/starlix. Targets functioning beta cells in pancreas to stimulate short-term insulin secretion. Rapid onset (1hour peak), short duration (4hours). Reduces postprandial BG. Take 0-30min before meal, NO MEAL NO MED
Repaglinide/prandin Non-sulfonylurea. Targets functioning beta cells in pancreas to stimulate short-term insulin secretion. Rapid onset (1hour peak), short duration (4hours). Reduces postprandial BG.
Nateglinide/starlix Non-sulfonylurea. Targets functioning beta cells in pancreas to stimulate short-term insulin secretion. Rapid onset (1hour peak), short duration (4hours). Reduces postprandial BG.
Non-sulfonylurea side effects Hypoglycemia, moderate weight gain, caution in those with liver failure or on dialysis, adherence issues
Created by: kat10
Popular Nursing sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards