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Leukemia Lymphoma

First Aid Leukemia Lymphoma

QuestionAnswer
Translocation associated with follicular lymphoma t(14,18); bcl-2 expression
Translocation associated with Burkitt's lymphoma t(8,14); c-myc expression
Translocation associated with mantle cell lymphoma t(11,14)
Translocation associated with CML t(9,22); Philadelphia chromosome, bcr-abl fusion
Translocation associated with Ewing's sarcoma t(11,22)
Translocation associated with M3 type AML t(15,17)
Lymphoma similar to CLL Small lymphocytic lymphoma
Most common lymphoma in adults Follicular lymphoma
Exhibits CD 5+ B cells and associated with poor prognosis Mantle cell lymphoma
Most common lymphoma of children Lymphocytic lymphoma
Starry sky appearance Burkitt's Lymphoma
Associated with monoclonal plasma cell with "fried egg" appearance and Bence Jones protein in urine Multiple myeloma
Most common leukemia of young children ALL
Most common leukemia of older adults CLL
Significant for Auer rods; peroxidase-positive cytoplasmic inclusions in granulocytes and myeloblasts AML
Leukemia most responsive to therapy ALL
Lymphoma with highest association with EBV Burkitt's lymphoma; also characteristic jaw lesion in endemic africa
Hyperviscosity syndrome which like multiple myeloma exhibits M spike of the IgM variety (instead of IgG) and has no lytic bone lesions Waldenstrom's macroglobulinemia
Distinctive tumor giant cell seen in Hodgkin's disease Reed-Sternberg cells; binucleate "owl's eyes" appearance
Commonly associated with smudge cells on blood smear, and warm antibody agglutination CLL
Created by: rahjohnson