Save
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Genetics - ABIM

Genetic abnormalities

QuestionAnswer
APC gene on 5q chromosome, mutation in familial adenomatous polyposis
5q gene deletion seen in MDS - 12 year prognosis, give lanalidomide; if in AML, this would be a poor prognosis and if young pt, should get allogenic BMT
5q gene mutation APC gene in FAP
what mutation do you see with APML which is a good prognostic factor? t(15,17)
RET protooncogne Medullary thyroid cancer
BRAF papillary thyroid cancer and hairy cell leukemia
RAS gene follicular thyroid cancer
t(15,17) acute promyelocytic leukemia, good prognosis
t(4,11) ALL
t(14,18) follicular small lymphotic lymphoma
cMYC gene Burkitt's lymphoma
t(8,14) Burkitt's
t(11,14) mantle cell lymphoma
17p13 deletion TP 53 - if present is a bad prognostic marker for CLL
t(9,22) CML
BCR/ABL fusion protein CML
B2 microglobulin tested in CLL, if >3.5 then only 1 year left
CD20 B-cell
JAK2 mutation found in 95% of patients with polycythemia vera and 50% to 60% of patients with essential thrombocythemia and primary myelofibrosis
JAK2 V617F - when should you order it? present in 97% with PV and in 50% of those with essential thrombocythemia and should be measured in all patients with Budd-Chiari syndrome. Positive findings indicate a myeloproliferative disorder and suggest the need for cytoreductive therapy.
t(8,21), what disease, what is the prognosis, what treatment AML Younger patients with favorable-risk cytogenetics (t(8;21), inv(16)) should receive high-dose cytarabine as consolidation therapy
CASR benign familial hypocalciuric hypercalcemia
Created by: christinapham
Popular USMLE sets
Goljan High Yield
First Aid: Microbiology 1
Hy - USMLE Buzzwords - One-Liners
First Aid: Microbiology 2
First Aid: Microbiology 3
First Aid: Microbiology 4
USMLE Step 1 Biochemistry
Classic Findings
Comprehensive Pharm 1
First Aid for USMLE Step 1 Rapid Review
First Aid: Antimicrobials
Comprehensive Pharm 3

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards