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PSYCHMEDS

2ND GENERATION

QuestionAnswer
2ND GENERATION/ATYPICAL ANTIPSYCHOTICS CLOZAPINE(CLAZARIL)USED AS A LAST RESORT FOR PEOPLE WITH RETRACTABLE PSYCHOSIS.S/E DROWSINESS, SEDATION, DIZZINESS, TACHYCARDIAPOSS FATAL S/EAGRANULOCYTOSIS, CONVULSIONS, NEUTROPHILS < 2000/ABSOL NEUTROPHILS <1000 D/C PERM
MOOD STABILIZERS LITHIUM, TEGRETOL(carbamazepine), DEPAKOTE (divalproex), LAMICTAL (lamotrigine), NEURONTIN (gabapentin), TOPAMAX (topiramate), KLONOPIN (CLONAZEPAM)**USED FOR BIPOLAR, MOOD CHANGES WITH MANIA AND PSYCOSIS
LITHIUM MOST ESTABLISHED STABILIZER, NORMALIZES REUPTAKE OF NT, REDUCES RELEASE OF NOREPI, ACTION OCCURS INTRACELLULARLY INSTEAD OF AT SYNAPSE, REQUIRES SERUM MONITORING
LITHIUM THEURAPEUTIC RANGE 0.6-1.2S/E: N/D ANOREXIA, FINE HND TREMOR, POLYURIA, POLYDIPSIA, METAL TASTE, FATIGUE, >WBC..LATER S/E: WGT GAIN, ACNE, ALOPECIA, COARSE TREMORS, CONFUSSION, SLURRED SPCH, SEDATION..EVENT LEADING TO: ARRITHYMIAS, SEIZURES, COMA, DEATH
LITHIUM TEACHING COMPLIANCE, SERUM LEVELS, TAKE WITH FOOD, HYDRATION, Na INTAKE SHOULD STAY AT LEVEL AS WHEN MED WAS THERAPEUTIC.HAND TREMORS...HOLD LITHIUM
SEROTONIN INHIBITS CATECHOLAMINE AND MEDIATES COGNITIVE EFFECTS, EMOTIONS DURING PANIC, MEMORY AND ANXIETY, VIOLENCE/AGGRESSION, SEXUAL FUNCTION, SLEEP/WAKE CYCLE
ANTIDEPRESSANTS TYPICAL/STANDARD ELAVIL (amitriptyline), TOFRANIL (imipramine)req bld level, PAMELOR (nortriptyline) req bld levelANTICHOLINERGIC S/E, CARDIAC S/E1980'SOD=DEATHNEEDS TO BE TAPERED OFF
ANTIDEPRESSANTS SSRI'S PROZAC (fluexetine)stim effect, ZOLOFT (sertraline), PAXIL (paroxetine), CELEXA (citalopram), LEXAPRO (escitaopram)1990'sOD=SEROTONIN SYNDROME
ANTIDEPRESSANTS MAOI'S MARPLAN(isocarvexazid), NARDIL(pheneizine), PARNATE(tranylcypromine)menoamine oxidase inhibitors MENOAMINES(NOREPI,EPI, DOPAMINE,TYRMINE)TRYPTOPHAN WILL INCREASE TYRAMINE WHICH >BP.DIETARY RESTRICTIONS: AGED,SMKD,FERM FOORS,ETOH,COFF,CHOC, MANY OTC MEDS
MAOI'S MUST BE D/C GRADUALLYORIGINALLY USED FOR TBPATIENT MUST BE COGNITIVELY AWARE ENOUGH TO FOLLOW DIET AND RESTRICTIONS
Created by: e0922
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