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Embryo
Question | Answer |
---|---|
Week 1 | BLASTOCYST implantation |
Week 2 | Bilaminar disk (epiblast & hypoblast) |
Week 3 | Gastrulation, primitive streak + notochord + Neural Plate |
Week 3-8 | Neural tube, Organogenesis, Teratogen susceptibility |
Week 4 | Heart beat, limb buds form |
Week 10 | Genital differentiation |
Alar plate | Sensory |
Basal plate | motor |
Adenohypophysis origin | Surface ectoderm |
Neuroectoderm Derivatives | CNS |
Neural Crest Derivatives | ANS, melanocytes, chromaffin & enterochromaffin, Pia & arachnoid, parafollicular C cells, laryngeal cartilage, skull |
Endoderm Derivatives | Gut tube & projecting organs + Thymus, Parathyroid, Thyroid |
Mesoderm Derivatives | Dura matter, CT, bone, muscle, heart, lymph, blood, urogenital & kidneys, serous lining, spleen, adrenal cortex |
Mesodermal defects | VACTERL: Vertebral, Anal atresia, cardiac, T-E Fistula, Renal, Limb (bone, muscle) |
Fetal Alcohol Syndrome | Inhibition of cell migration -> development retardation, microcephaly, facial abnormalities, limb dislocation, heart & lung fistulas |
ACE inhibitors | Renal damage |
Cocaine | Development abnormalities & addiction |
Iodide | Goiter, hypothyroid |
Vitamin A | Birth defects |
Thalidomide | Limb defects “flipper” |
Tobacco | Preterm, placental probs, ADHD |
Warfarin, x-rays, anticonvulsants | Multiple anomalies |
Right cardinal vein | SVC |
Left horn of Sinus Venosus | Coronary Sinus |
Hemoglobin A | Spleen from wk 9-28, bone marrow afterwards |
Hemoglobin F | Liver, week 6-30 |
Ligamentum teres hepatis (in falciform lig) | Umbilical vein |
Branchial/Pharyngeal Arch 1 | Mandible + Muscles of mastication, inferior jaw (Mylohyoid & ant belly of digastric. Inner Ear: Malleus, incus + tensor tympani/veli palatini. Anterior tongue. CN V2, 3 |
Branchial/Pharyngeal Arch 2 | STAPES, styloid, anterior hyoid, stylohyoid ligament & muscle, posterior digastric, Facial expression muscles. CN 7 |
Branchial/Pharyngeal Arch 3 | Greater Hyoid, stylopharyngeus. CN 9, posterior tongue (w/#4) |
Branchial/Pharyngeal Arch 4 | Pharyngeal constrictors, levator veli palatini, posterior tongue (w/#3). Superior laryngeal CN 10. w/6: Cartilage of the throat: corniculate, cuneiform, arytenoids, cricoid, thyroid. |
Branchial/Pharyngeal arch 6 | Intrinsic laryngeal muscles (minus cricothyroid). Recurrent laryngeal CN 10. w/4: Cartilage of the throat: corniculate, cuneiform, arytenoids, cricoid, thyroid. |
1st Branchial/Pharyngeal cleft & pouch | 1st Cleft: External auditory meatus. 1st Pouch: Middle ear, eustachian tube |
2nd Branchial/Pharyngeal Pouch | Palatine tonsils |
3rd Branchial/Pharyngeal Pouch | Dorsal: Inferior Parathyroid. Ventral: Thymus |
4th Branchial/Pharyngeal Pouch | Superior parathyroid |
Tongue Innervation | Ant 2/3- Taste CN 7, Sensory CN V3. Posterior 1/3: Taste & sensation CN9,10. Motor CN 12 |
Urogenital Sinus Derivatives | Male: Corpus spongiosum, bulbourethral/Cowper’s glands, prostate glands. Female: Vestibular bulbs, Bartholin glands, Urethral & paraurethral glands (of skene) |
Urogenital Fold Derivatives | M: Ventral shaft of penis. F: Labia Minora |
Genital Tubercle | Glans penis, clitoris |