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Metabolism
Aerobic, anaerobic, proteins and lipids
| Question | Answer |
|---|---|
| Aerobic Respiration | breakdown of glucose in the presence of O2 to produce CO2, H2O, 36/38 ATP |
| Phases of Aerobic Respiration | Glycolysis, Transition Reaction, Kreb's Cycle, Electron Transport Chain |
| Glycolysis | Requires ATP. Doesn't need O2. Cell lysis glucose (6 carbon) to pyruvate (3 carbon). H removed and slowly accepted by NAD. |
| Site of Glycolysis | Cytoplasm |
| Glycolysis Yield | Yields 2 ATP (2 in, 4 out). FINAL YIELD = 2 atp, 2 nadh, 2 pyruvate |
| Transition Rxn | Needs O2. |
| Site of Transition Rxn | Matrix of mitochondria |
| Transition Rxn Yield | 0 atp, H removed, accepted by NAD. 2 carbons removed. FINAL YIELD = 2 coenzyme A, 2 NADH, 2 CO2 |
| Kreb's Cycle | Needs O2. 2 ATP produced by Substrate Phosphorylation. 4 carbons removed. H accepted at various stages by NAD and FAD. |
| Site of Kreb's Cycle | Matrix of mitochondria |
| Kreb's Cycle Yield | FINAL YIELD = 2 atp, 6 nadh, 2 fadh2, 4 co2 |
| Electron Transport Chain | Needs O2. 32/34 ATP produced by Oxidative Phosphorylation. H is transferred from NADH and FADH2 in first 3 stages to electron acceptor in mitochondria. Electrons from H rel. energy from one energy level to the next. Low energy electrons accepted by O2. |
| Site of Electron Transport Chain | Cristae of mitochondria |
| Electron Transport Chain Yield | 32/34 ATP. NADH = 3 ATP, FADH2 = 2 ATP. Sometimes NADH is reduced yielding 32 instead of 34 ATP. |
| Anaerobic Respiration | Breakdown of glucose in the absence of O2. |
| Phases of Anaerobic Respiration | Glycolysis (2 atp, 2 nadh, 2 pyruvic acid), Lactic acid converted from pyruvic acid |
| Anaerobic Respiration Yield | FINAL YIELD = 2atp, 2 nadh, 2 lactic acid |
| Conversion of lactic acid | Lactic acid goes to the liver, where it undergoes the Kreb's Cycle to be reconverted into pyruvic acid |
| Lipid Metabolism | Triacylglycerol -> glycerol + fatty acid. glycerol --glycolysis--> Acetyl CoA. fatty acids --Beta oxidation--> Acetyl CoA which enters Kreb's Cycle. Acetyl CoA can be used to produce Ketone bodies (keto acids). |
| Protein Metabolism | New AA formed by transamination. AA are used to syntehsize proteins. AA can be used as energy but NH3 and Keto acids are produced. |
| Transamination | Transfer of an amine group to a keto acid. |
| Glycogenesis | Formation of glycogen from glucose |
| Lipogenesis | Formation of lipids from glucose and amino acids |
| Glycogenolysis | Breakdown of glycogen to glucose |
| Gluconeogenesis | Formation of glucose from amino acids and glycerol |
| Metabolic States | Absorptive, Postabsorptive |
| Absorptive State | nutrients are used as energy or stored |
| Postabsorptive State | Stored nutrients are used for energy |
| Structure of Glucose | C6 H12 O6 |