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HCTA Pharmacology Q1
HCTA/NESPN Pharmacology Quiz 1
| Question | Answer |
|---|---|
| Fat Solu. Vit's ? | Fat Solu Vit: A,D,E, & K |
| H2O Solu. Vit's ? | H2O Solu Vit: B-complex, C, Niacin, Riboflavin, Thiamine, Nicotinic Acid, Pyridoxine (Vit B6). |
| Which type of vit's will lead to toxicity? | Fat Solu Vit's can build up in the system and become toxic. |
| Mineral Used to Help Control Diabetes? | Mineral for DM: Chromium |
| Which type of oral med is most quickly absorbed? | >Orally Abs Med type: Liquid Forms |
| What does food tend to do to absorption of meds (Generally Speaking) ? | Food: Tends to Slow the Abs of Meds from the GI tract. It can change production levels of gastric acid, bind with drugs, and disrupt distribution access to the linings of GI tract for drug absorption. In some case, HCL can degrade meds. |
| Which types of Meds cross easiest via GI membranes? | GI membranes Med Abs: Membrane is a Lipid, so Lipid Soluble drugs tend to pass more rapidly across lipid membranes. |
| What do Water Solu Drugs require to be transported in system? | Water Solu Meds: Req'r a "Carrier", Enzyme or Protien. |
| How is Passive Absorption done? | Passive Abs: mostly done by "Diffusion" |
| What is "Active" Absorption? | Active Absorption: Req'r Carrier, Energy (ATP), can be via Pinocytosis (lg'r med molecules). *Weakly Charged (less charge/non-ionized) lipid solu pass thru stomach lining more rapidly than H2O solu meds. Example: ASA. |
| What is "First Pass Effect"? | First Pass: Meds tend to pass thru liver where they are metabolized into either their active form, or are degraded and potency is lost. When deactivation occurs in liver by first pass the inactive forms usually become H2O solu and bass out thru Kidney, o |
| What are binding levels for Protien Bound Meds? | Protien Binding: High (>89%), Mod-High (61-89%), Moderate (30-60%), Low (<30%) |
| What is the medically active state for Protein-Bound medication? | Protien-Bound Drugs are Not Medical Active as they are not accessable to link with receptor sites, therefore the active form of highly protien-bound drugs would only occur when they are in their "Free" form, or when not actually bound to protiens. The am |
| What happens if Protein Plasma/Albumin levels decrease in Pt taking a highly protein-bound med? | If plasma protien/albumin levels drop in pts taking highly protein-bound meds they may experience drug toxicity or increased effects of med because more of the drug is in circulation and not bound to protiens. |
| What is the Half-Life definition for medications? | Half-Life: Time it takes for 1/2 of drug to be eliminated from system. |
| Where is the major site/organ of drug elimintation? | Major Organ site for Drug Elimination: Kidneys (Free unbound meds, H2O solu, or unchanged H20 solu meds in system filter out via kidneys. Protein-Bound & non-H20 solu meds are not filtered out by glomerulus filtration and thus are not excreated). |
| What are general dosing freq's for diff Half-Life Meds? (What is dosing for drug with T 1/2 of 72 hrs? asked on quiz 1) | Long T 1/2 (q.12h), Short T 1/2 (q.4-8h), ***Long'r T 1/2 may be > q.24h*** See p. 9 Pharmacology: A Nursing Process, 5th Ed. ***For Med w/T 1/2 = 72 hrs dosing given q.12h according to Teacher. |
| Normal Creatinine Levels? | Norm. Creatinine: (85-135 ml/min. Excreation Rate *?*), and (0.5-1.5 mg/dL for Serum Creatinine Levels) **See Page 6-7 in Book. |
| Enzyme Inducers (According to Teacher, in General) will do what? | Enzyme Inducers: Stimulate *While, Inhibitors slow down enzymatic reactions. |
| What do you look for when purchasing Herbal/OTC products? | Herbal/OTC Purchasing: Scientific Name, Manufacturer's Name & Address, Manufacturing Date, Expiration Date, Batch/Lot # should be on package. *Standardized Strengths of Content may varry, or lack of standardization of Content in many cases. |
| How are Clotting times affected by Ginko, Garlic, & St. John's Wort? | Clotting Times: Ginko ( ), Garlic ( ), St. John's Wort ( ) |
| Know how to do med calculations, and know conversions... | Bring Calculator for Quizes and Exams... |
| How many pounds (US Wt.) in one Kilogram (1,000 grams, or 1 kg.) ? | 2.2 lbs = 1 kg. |
| What is the therapuetic dose range for Dilantin? | Dilantin Range (10-20...) |
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