Save
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Agonist/Antagonists

Pharm (Test 2)

QuestionAnswer
Describe the receptor affinity of Pentazocine (Talwin). weak mu antagonist, partial kappa agonist
What are the indications for Pentazocine (Talwin)? moderate pain, chronic pain, inc. risk of physical dependence
What are the effects of Pentazocine (Talwin)? analgesia, sedation, mild resp. depression
Describe the CV effects of Pentazocine (Talwin). inc. HR, cardiac workload, SBP, PA pressure, and myocardial O2 consumption
What patients have special considerations for the use of Pentazocine (Talwin)? IHD, CHF, MI, pregnant mothers
Does narcan antagonize Pentazocine (Talwin)? yes
Does Pentazocine (Talwin) antagonize resp. depression? no
Describe the receptor affinity of Butorphanol (Stadol). more kappa than mu or sigma
Compare potency between Talwin and Stadol. Stadol is 20X more agonist potent and 10-30X more antagonist potent than Talwin
Compare analgesic potency between Butrophanol (Stadol) and morphine. stadol has more analgesic potency than morphine
What are the indications of Butrophanol (Stadol)? post-op pain, migraine headaches, post-op shivering
What are the effects of Butrophanol (Stadol)? analgesia, resp. depression
What are some side effects of Pentazocine (Talwin)? (DD) sedation, dysphoria, diaphoresis, dizziness, dissociation, "weird" feelings, hallucinations, NO mood elevation
What are some side effects of Butorphanol (Stadol)? withdrawal after d/c, sedation, nausea, diaphoresis, resp. depression, dissociation, dysphoria is RARE
Describe the CV concerns with Butrophanol (Stadol). inc. CO, cardiac workload, SBP and PA pressure
What patients have special considerations for the use of Butrophanol (Stadol)? CHF and MI pts
Which agonist/antagonist has a nasal spray? Stadol
Describe the receptor affinity of Nalbuphine (Nubain). mu antagonist, kappa agonist
Compare the potency of Nalbuphine (Nubain) to morphine. very comparable
What are the indications for use of Nalbuphine (Nubain)? reversing fent-induced resp. dep; antagonizes pruritis induced by epidural morphine
What are the effects of Nalbuphine (Nubain)? kappa provide adequate pain relief w/ less resp. depression, analgesia, sedation
What are the side effects of Nalbuphine (Nubain)? withdrawal after d/c, diaphoresis, headache, dissociation
Describe the CV concerns for Nalbuphine (Nubain). none
Does narcan antagonize stadol? no
Does narcan antagonize Nubain? yes
True or False: Nalbuphine (Nubain) has a ceiling for respiratory depression. True
Describe the receptor affinity of Buprenorphine (Buprenex). partial mu agonist, mu antagonist
Describe the receptor affinity of Buprenorphine (Buprenex) to that of morphine. Buprenex's affinity for mu receptor is 50X greater than morphine
What are the indications for use of Buprenorphine (Buprenex)? reversing fent-induced resp. dep; effective on moderate to severe cancer pain; opioid dependence
What are some side effects of Buprenorphine (Buprenex)? withdrawal after d/c, sedation, n/v, diaphoresis, headache, dizziness
Does narcan antagonist Buprenorphine (Buprenex)? no
Which a/a can treat migraine headaches? stadol
Which a/a(s) can be used to treat fent-induced resp. dep? nubain, buprenex
Which a/a(s) can cause withdrawal after d/c? stadol, nubain, buprenex
Which a/a(s) cause inc. HR, SBP, cardiac workload, etc? talwin, stadol
Which a/a(s) can be antagonized by narcan? talwin, nubain
Which a/a is available in a nasal spray? stadol
Which a/a has a potency comparable to morphine? nubain
Which a/a has a ceiling resp. depressant effect? nubain
Which a/a can cross the placental barrier and cause fetal depression? talwin
Which a/a(s) are kappa agonists? talwin, stadol, nubain
Which a/a can cause "weird" feelings and hallucinations? talwin
Which a/a is effective for cancer pain? buprenex
Which a/a has a mu receptor affinity 50X greater than morphine? buprenex
Which a/a has analgesic potency greater than morphine? stadol
Which a/a can be used to treat post-op shivering? stadol
Which a/a antagonizes the pruritis induced by epidural morphine? nubain
Popular Nursing sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards