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Pharm
| Question | Answer |
|---|---|
| Patient has been drinking and experiencing with prescription drugs and now presents comatose. Patient most likely overdosed on? | Benzodiazepine- Lorazepam. co-ingestion with alcohol will cause severe CNS depression |
| Medication for anxiety | Benzo- Lorazepam |
| benzodiazepine antagonist (reverse signs of benzo overdose) | Flumazenil |
| inhibits cGMP breakdown-> prolonged vasodilation->prolonged erection | Sildenafil and vardenafil |
| 5HT reuptake inhibitors SSRI | Fluoxetine, Paroxetine, Sertraline, Citalopram (Flashbacks paralyze senior citizens) |
| Treat depression, OCD, PTSD | SSRI |
| OCD | DOC: SSRI- Fluoxetine Other: TCA- Clomipramine |
| What teratogen causes congenital goiter or hypothyroidism (cretinism) | iodine |
| teratogen- renal damage | ACE inhibitors |
| teratogen- bone deformeions, fetal hemorrhages | Warfarin |
| teratogen- discolored teeth | tetracyclines |
| teratogen- neural tube defect, fingernail hypoplasia | carbamazepine |
| teratogen- neural tube defect | folate antagonists |
| teratogen- ebstein anomaly (atrialized right ventricle) | litium |
| teratogen- inhibition of maternal folate absorption | valproate |
| Closes PDA | Indomethacin |
| keeps PDA open | prostoglandins E1 and E2 |
| Prolactinoma | dopamine agonist: Bromocriptine or cabergoline |
| Acromegaly | Somatostatin analog: octreotide |
| Hyperthroidism | Propylthiouracil (used in preg; hepatotoxicity) & methimazole |
| Hypothyrodism | Levothyroxine (T4; cardiotoxicity) or triidothyronine (T3) |
| Blocks both peroxidase and 5'-deiodinase | PTU |