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Chronic Neurologic Disorder Medication: neostigmine (Prostigmin)

What is the prototype drug for this class? neostimine (Prostigmin)
What conditions is this medication used to treat? (2) Myasthenia Gravis & Parkinson's Disease
How does this medication help those with Myasthenia Gravis & Parkinson's Disease? (2) To manage symptoms & improve quality of life
How does this medication work? Prevents the enzyme cholinesterase from inactivating acetylchoine
What results come from the inactivation of acetylcholine? An increase in the amount of acetycholine available to receptor sites
What is this drug used to treat? (2) 1.) myasthenia gravis 2.) reversal of neuromuscular blocking agents
What is the main adverse effect caused by this drug & what symptoms arise (3)? Parasympathetic NS effects (diarrhea, bradycardia, urinary urgency)
Cholinergic crisis (2) Parasympathetic effects & respiratory depression
What can respiratory depression lead to? (2) Respiratory arrest OR cardiac failure
What pregnancy category is this drug? C
What is the antidote used to treat neostigmine adverse effects (SNS)? Atropine
What would be present if the patient were going into respiratory depression? (3) 1.) Respiratory rate below 12 2.) Cyanotic 3.) SpO2 below 94%
When should you use this medication cautiously? (5) 1.) Seizures 2.) PUD 3.) Asthma (causes bronchoconstriction) 4.) bradycardia 5.) hypotension
When would you NOT give this medication? If the patient had obstructive disorders
What do you monitor when giving Atropine? (3) 1.) BP 2.) pulse 3.) Respirations (before & AFTER administration)
Instruct patient to take this medication ______ As prescribed
What is a usual dose routine for this medication? Start with a LOW dose & then TITRATE
When titrating this medication, how will you know when you have reached therapeutic levels? When the desired muscle function is achieved
When should you take this medication? (2) 1.) At the SAME time each day 2.) In the morning
What should you suggest your patient do while taking this medication? Advise them to KEEP A JOURNAL.
What should you educate your patient to record in the journal? (5) 1.) How it's making them feel 2.) How are they able to do their ADLs? 3.) Any adverse effects? 4.) Difficulty swallowing? 5.) Urinary urgency
The patients' journal should let the nurse know... If the medication is working
How would the nurse know if the medication is working? The patients' ability to do their ADLs should improve. If not, slowly increase dose
What should the nurse educate the patient to wear? A medic alert bracelet
How would the nurse evaluate improvement with this medication? 1.) Strength in chewing 2.) Swallowing 3.) Performing ADLs
Created by: amydawsonpool13