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Prostigmin
Chronic Neurologic Disorder Medication: neostigmine (Prostigmin)
| Question | Answer |
|---|---|
| What is the prototype drug for this class? | neostimine (Prostigmin) |
| What conditions is this medication used to treat? (2) | Myasthenia Gravis & Parkinson's Disease |
| How does this medication help those with Myasthenia Gravis & Parkinson's Disease? (2) | To manage symptoms & improve quality of life |
| How does this medication work? | Prevents the enzyme cholinesterase from inactivating acetylchoine |
| What results come from the inactivation of acetylcholine? | An increase in the amount of acetycholine available to receptor sites |
| What is this drug used to treat? (2) | 1.) myasthenia gravis 2.) reversal of neuromuscular blocking agents |
| What is the main adverse effect caused by this drug & what symptoms arise (3)? | Parasympathetic NS effects (diarrhea, bradycardia, urinary urgency) |
| Cholinergic crisis (2) | Parasympathetic effects & respiratory depression |
| What can respiratory depression lead to? (2) | Respiratory arrest OR cardiac failure |
| What pregnancy category is this drug? | C |
| What is the antidote used to treat neostigmine adverse effects (SNS)? | Atropine |
| What would be present if the patient were going into respiratory depression? (3) | 1.) Respiratory rate below 12 2.) Cyanotic 3.) SpO2 below 94% |
| When should you use this medication cautiously? (5) | 1.) Seizures 2.) PUD 3.) Asthma (causes bronchoconstriction) 4.) bradycardia 5.) hypotension |
| When would you NOT give this medication? | If the patient had obstructive disorders |
| What do you monitor when giving Atropine? (3) | 1.) BP 2.) pulse 3.) Respirations (before & AFTER administration) |
| Instruct patient to take this medication ______ | As prescribed |
| What is a usual dose routine for this medication? | Start with a LOW dose & then TITRATE |
| When titrating this medication, how will you know when you have reached therapeutic levels? | When the desired muscle function is achieved |
| When should you take this medication? (2) | 1.) At the SAME time each day 2.) In the morning |
| What should you suggest your patient do while taking this medication? | Advise them to KEEP A JOURNAL. |
| What should you educate your patient to record in the journal? (5) | 1.) How it's making them feel 2.) How are they able to do their ADLs? 3.) Any adverse effects? 4.) Difficulty swallowing? 5.) Urinary urgency |
| The patients' journal should let the nurse know... | If the medication is working |
| How would the nurse know if the medication is working? | The patients' ability to do their ADLs should improve. If not, slowly increase dose |
| What should the nurse educate the patient to wear? | A medic alert bracelet |
| How would the nurse evaluate improvement with this medication? | 1.) Strength in chewing 2.) Swallowing 3.) Performing ADLs |
Created by:
amydawsonpool13
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