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Neuromuscular Blocking Agents

What is the prototype drug for neuromuscular blocking agents? succinylcholine (Anectine)
What is their purpose? What does this cause (2)? To block acetylcholine (ACh) at the neuromuscular junction, causing muscle relaxation & hypotension
Benefit of neuromuscular blocking agents? Do NOT cross the blood-brain barrier, allowing PARALYSIS withOUT loss of consciousness
Therapeutic Uses (4) 1.) Used as adjunct to general anesthesia to promote muscle relaxation 2.) mechanical ventilation 3.) seizure control 4.) during intubation & endoscopies
Major adverse effect? Malignant hyperthermia
If signs of malignant hyperthermia present...(4) 1.) STOP medication 2.) administer 100% oxygen 3.) Initiate cooling measures 4.) Administer DANTROLENE
What lab value needs to be monitored? Potassium...this medication can cause hyperkalemia
What are the TWO main organs we are concerned with while taking this medication? HEART & LUNGS! This medication can cause HTN/bradycardia & respiratory arrest
A patient taking this medication should ALWAYS be on... A HEART monitor!
How often do we assess vitals while this patient is taking this medication? Every FIVE minutes
What pregnancy category is this medication? C
After surgery, it is important to monitor the patient for... Return of respiratory function & movement. This medication can cause respiratory arrest!
Created by: amydawsonpool13