Save
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Respiratory Pharm

Stack #175401

DrugMOA/UseToxicity/adverse effects
H1 blockers, 2nd generation: loratadine, fexofenadine, desloratadine, cetirizine reversible inhibitors of H1 receptors; use: allergy far less sedating than 1st generation because of decreased entry into CNS
isoproterenol nonspecific beta-agonists: relaxes bronchial smooth muscle (beta2) tachycardia (beta1)
albeterol (beta2 agonist)relaxes bronchial smooth muscle (beta2); use: acute asthma exascerbation
salmeterol beta2 agonist; long acting agent for asthma prophylaxis tremor and arrhythmia
Methylxanthines: theophylline likely causes bronchodilation by inhibiting phosphodiesterase, thereby decreasing cAMP hydrolysis. Usage is limited because of narrow therapeutic index; metabolized by P450; Use: asthma cardiotoxicity, neurotoxicity
Muscarinic antagonists: Ipratroprium competative block of muscarinic recptors, preventing bronchoconstriction; use:asthma, COPD
cromolyln prevents release of mediators from mast cells. effective only for prophylaxes of asthma. not effective for acute asthma attack. toxicity is rare
corticosteroids: beclomethasone, prednisone inhibit sythesis f virtually all cytokines. Inactivate NF-kB, the transcription factor that induces the production of TNF-alpha, among other inflammatory agents. 1st-line therapy for chronic asthma.
zileuton antileukotriene: a 5-lipoxygenase pathway inhibitor. blocks conversion of arachidonic acid to leukotrienes.
zafirlukast, montelukast antileukotrienes; block leukotriene receptors. especially good for aspirin-induced asthma.
guaifenesin (robitussin) expectorants; removes excess sputum but large doses necessary; does not suppress cough reflex.
N-acetylcysteine expectorant: mucolytic->can loosen mucous plugs in CF patients. also used as an antidote for acetaminophen overdose.
H1 blockers, 1st generation: diphenhydramine, dimenhydrinate, chlorpheniramine reversible inhibitors of H1 receptors; use: allergy, motion sickness, sleep aid sedation, antimuscarinic, anti-alpha-adrenergic
Created by: hazelett
Popular USMLE sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards