Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
Know
remaining cards
Save
0:01
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards
share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Respiratory Pharm

Stack #175401

DrugMOA/UseToxicity/adverse effects
H1 blockers, 2nd generation: loratadine, fexofenadine, desloratadine, cetirizine reversible inhibitors of H1 receptors; use: allergy far less sedating than 1st generation because of decreased entry into CNS
isoproterenol nonspecific beta-agonists: relaxes bronchial smooth muscle (beta2) tachycardia (beta1)
albeterol (beta2 agonist)relaxes bronchial smooth muscle (beta2); use: acute asthma exascerbation
salmeterol beta2 agonist; long acting agent for asthma prophylaxis tremor and arrhythmia
Methylxanthines: theophylline likely causes bronchodilation by inhibiting phosphodiesterase, thereby decreasing cAMP hydrolysis. Usage is limited because of narrow therapeutic index; metabolized by P450; Use: asthma cardiotoxicity, neurotoxicity
Muscarinic antagonists: Ipratroprium competative block of muscarinic recptors, preventing bronchoconstriction; use:asthma, COPD
cromolyln prevents release of mediators from mast cells. effective only for prophylaxes of asthma. not effective for acute asthma attack. toxicity is rare
corticosteroids: beclomethasone, prednisone inhibit sythesis f virtually all cytokines. Inactivate NF-kB, the transcription factor that induces the production of TNF-alpha, among other inflammatory agents. 1st-line therapy for chronic asthma.
zileuton antileukotriene: a 5-lipoxygenase pathway inhibitor. blocks conversion of arachidonic acid to leukotrienes.
zafirlukast, montelukast antileukotrienes; block leukotriene receptors. especially good for aspirin-induced asthma.
guaifenesin (robitussin) expectorants; removes excess sputum but large doses necessary; does not suppress cough reflex.
N-acetylcysteine expectorant: mucolytic->can loosen mucous plugs in CF patients. also used as an antidote for acetaminophen overdose.
H1 blockers, 1st generation: diphenhydramine, dimenhydrinate, chlorpheniramine reversible inhibitors of H1 receptors; use: allergy, motion sickness, sleep aid sedation, antimuscarinic, anti-alpha-adrenergic
Created by: hazelett