Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.

By signing up, I agree to StudyStack's Terms of Service and Privacy Policy.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.

Remove ads
Don't know
remaining cards
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards

Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Cell Bio Exam 3

Ch 15, 17, 18, 21

Properties of Intermediate Filaments Polarity: None Functions: -Structure -Shape -Formation of nuclear lamina and scaffolding -Strengthening of nerve cell axons -Keeping muscle fibers in register
Properties of Microtubules Monomers: Alpha-Tubulin and Beta-Tubulin Polarity: +/- ends Functions: -Organization of share and polarity -Chromosome movements -Intracellular transport -Cell motility
Elements of the Cytoskeleton 1. Microtubules (MTs) 2. Microfilaments (MFs) 3. Intermediate filaments (IFs)
Properties of Microfilaments Monomers: G-actin Polarity: +/- ends Functions: -Muscle contraction -Cell locomotion -Cytoplasmic streaming -Cytokinesis -Shape and transport
Types of Microtubules 1. Cytoplasmic 2. Axonemal
Bacterial-Tubulin Equivalent Ftz
Bacterial Intermediate Filament Protein Equivalent Crescentin
Protofilament, Heterodimer, Tubulin Monomers Protofilament: The whole heterodimer and monomer(alpha or beta monomers) all together. Heterodimer: Alpha and Beta monomers. Monomer: An alpha or Beta particle.
Bacteria Actin Equivalent MreB
Vinblastine and Vincristine -Affect MTs -Aggregate tubulin heterodimers
Phallodin -Affects MFs -Binds and stabilizes assembled MFs - (+) No polymerization - (-) No depolymerization
Taxol - Affects MTs - Stabilizes MTs - (+) No polymerization - (-) No depolymerization -Everything is stable.
Latrunculin A - Affects MFs - Sequesters actin monomers "JAIL" (Puts monomers separately in a corner or "jail" to keep from polymerizing.
Microfilament Actins - G-actin - F-actin - G-actin: Monomers of F-actin - F-actin: Polymerized G-actin which form filaments.
Cytochalasin D - Affects MTs - Prevents addition of new monomers to plus ends ("thinks plus end is ugly and won't hook up with it")
Colchicine Colcemid - Affects MTs - Binds tubulin monomers, inhibiting self assembly (binds to both/either alpha or beta monomers and won't let them polymerize).
Nocadazole - Affects MTs - Binds to Beta-tubulin, inhibiting polymerization (thus will not allow the monomers to bind).
Singlet MTs - 13 profilaments - Cytoplasmic MTs
Doublet MTs - One of the 13 protofilament part and one additional incomplete 10 or 11 protofilament part. - Ex: Cilia and flagella
Triplet MTs - One 13 protofilament part and two additional 10 or 11 protofilament parts. - Ex: Basal bodies and centrioles
Microtubule Nucleation - When oligomers (groups of aggregated tubulin heterodimers) form nuclei from which MTs grow.
Microtubule Elongation - The stage in which nucleated MTs grow by the addition of subunits at either end.
MT Lag Phase Nucleation
MT Elongation Phase - Tubulin heterodimers are added to the nucleated MT and it grows.
MT Plateau Phase - MT assembly and disassembly are balanced.
MT Critical Concentration - The tubulin heterodimer concentration at which MT assembly is exactly balanced with disassembly.
MT Plus End - The rapidly growing end of the MT.
MT Minus End - The slowly growing end of the MT OR - The depolymerizing end when the critical concentration is reached for the plus end, but not the minus end.
Treadmilling - When a given tubulin molecule incorporated at the plus end is displaced progressively along. -The MT eventually are lost by depolymerization at the opposite end.
MAPs -MT-associated proteins. -MAPs increased MT stability and can affect the density of bundles of MTs. -Tau: Causes MTs to form tight bundles in axons. -MAP2: Causes the formation of looser bundles of MTs.
Tau Causes MTs to form tight bundles in axons.
MAP2 Causes the formation of looser bundles of MTs.