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glomerualr disease

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QuestionAnswer
Injury to the glomerulus is often reflected by the presence of what two things in the urine blood (hematuria) or protein (proteinuria)
type of glomerluar disease, This is characterized by hematuria, red blood cell casts, azotemia, hypertension, and oliguria NEPHRITIC SYNDROME
In general, these disorders are immunologically mediated. NEPHRITIC SYNDROME
This may occur at any age but is most commonly seen in children 1-3 weeks after a Group A ß-hemolytic streptococcal infection (usually strep throat) ACUTE PROLIFERATIVE (POST-INFECTIOUS) GLOMERULONEPHRITIS
Acute proiferative lomerulonephritis is due to antigen-antibody complexes (Type III immune hypersensitivity reaction) getting trapped in glomeruli. These complexes damage the basement membranes of the glomerular capillaries
what is the endresult of the basement membranes ofthe glomerular capillariesbeing damaged with acue proliferatie glomerulonephritis? blood and protein to escape into the urine collecting system.
Symptoms of what type of glomerular disease? In children, there is malaise, fever, oliguria, hematuria, nausea, periorbital edema, and mild-moderate hypertension. NEPHRITIC SYNDROME
What presents in the urine of a child ith acute proliferative glomerulonephriti? Red blood cell casts (red blood cells trapped in a protein matrix) and mild amounts of protein (< 1 gm) are present in the urine.
What percent of children recover fully while a few may progress to chronic glomerulonephritis. 95
The prognosis in adults with acute proliferatie glomerulonephritis is a little poorer with about recovery. 60
This is a clinicopathologic syndrome in which there is a rapid progression to renal failure RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS (RPGN) -
what is the length from onset to renal failure in clients with rapidly progressive gloerulonephritis? weeks
The following are symptoms of what type of glomeulonephrtis?his may have an abrupt onset of oliguria and hematuria with lesser degrees of hypertension, edema, and proteinuria. rapidly progressive
This is a constellation of signs characterized by proteinuria (> 3.5 gm/day), hypoalbuminemia (reversed albumin:globulin ratio), hyperlipidemia (increased LDL and/or VLDL), lipiduria (free fat and oval fat bodies in urine), and edema (pitting edema mos NEPHROTIC SYNDROME
proteinuria, what is numerical value (> 3.5 gm/day),
Complications of nephrotic syndrome include infections (due to loss of immunoglobulins and complement) and thrombosis (due to loss of anticoagulant factors)
The major diseases causing the nephrotic syndrome are: MINIMAL CHANGE DISEASE (lipoid nephrosis, nil disease),MEMBRANOUS GLOMERULONEPHROPATHY
This is the most common cause of nephrotic syndrome in children, but it can occur in adults as well. MINIMAL CHANGE DISEASE (lipoid nephrosis, nil disease) -
Children with minimal change disease respond to what type of therapy? steroid
This is the most common cause of nephrotic syndrome in adults (usually young to middle aged) MEMBRANOUS GLOMERULONEPHROPATHY -
type ofnephrotic syndrome, characterized by thickening of the glomerular capillary basement membranes. memranous glomerulonephopathy
What are three symptoms f membanous glomerlonephropathy? develop increasing blood urea nitrogen (BUN), hypertension, and progressive renal failure.
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